INT75629

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Context Info
Confidence 0.66
First Reported 1998
Last Reported 2011
Negated 0
Speculated 2
Reported most in Body
Documents 41
Total Number 43
Disease Relevance 8.19
Pain Relevance 4.51

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoskeleton (Mtap2) intracellular (Mtap2) protein complex (Mtap2)
cytoplasm (Mtap2)
Anatomy Link Frequency
glial cells 6
neurons 6
brain 2
brainstem 2
hippocampus 2
Mtap2 (Mus musculus)
Pain Link Frequency Relevance Heat
gABA 28 99.64 Very High Very High Very High
Hippocampus 203 99.54 Very High Very High Very High
Spinal cord 103 99.52 Very High Very High Very High
medulla 57 99.48 Very High Very High Very High
interneuron 30 98.96 Very High Very High Very High
imagery 51 95.88 Very High Very High Very High
Neuritis 4 95.88 Very High Very High Very High
Root ganglion neuron 1 93.92 High High
Dopamine 7 93.72 High High
Enkephalin 2 92.04 High High
Disease Link Frequency Relevance Heat
Infection 67 98.96 Very High Very High Very High
Disseminated Intravascular Coagulation 42 98.66 Very High Very High Very High
Targeted Disruption 469 97.52 Very High Very High Very High
Gliosis 6 96.28 Very High Very High Very High
Neuritis 4 95.88 Very High Very High Very High
Death 166 95.80 Very High Very High Very High
Ganglion Cysts 57 94.32 High High
Graft Vs Host Disease 11 94.08 High High
Neurodegenerative Disease 102 89.20 High High
Urological Neuroanatomy 16 84.88 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Double staining with DHE and monoclonal antibody against MAP2 showed that most cells positive for DHE were also positive for MAP2.
Gene_expression (positive) of MAP2
1) Confidence 0.66 Published 2008 Journal Neurol. Med. Chir. (Tokyo) Section Abstract Doc Link 19106491 Disease Relevance 0.25 Pain Relevance 0.12
A subpopulation of the GFP immunoreactive cells was clearly found to co-express MAP2ab (microtubule-associated protein 2 which is found in mature neurons) and GFAP (glial fibrillary acid protein present in glial cells).
Gene_expression (express) of MAP2ab in glial cells
2) Confidence 0.65 Published 2010 Journal Acta Histochemica et Cytochemica Section Body Doc Link PMC3015049 Disease Relevance 0.08 Pain Relevance 0
A subpopulation of the GFP immunoreactive cells was clearly found to co-express MAP2ab (microtubule-associated protein 2 which is found in mature neurons) and GFAP (glial fibrillary acid protein present in glial cells).
Gene_expression (express) of microtubule-associated protein 2 in glial cells
3) Confidence 0.65 Published 2010 Journal Acta Histochemica et Cytochemica Section Body Doc Link PMC3015049 Disease Relevance 0.08 Pain Relevance 0
In Figures 3A–F, the transplanted ADSC in the GCL expressed MAP2ab, while the transplanted ADSC in the vitreous chamber expressed MAP2ab in Figures 3G–I.
Gene_expression (expressed) of MAP2ab in vitreous chamber
4) Confidence 0.65 Published 2010 Journal Acta Histochemica et Cytochemica Section Body Doc Link PMC3015049 Disease Relevance 0.13 Pain Relevance 0
In addition, mBPC expressed MAP2 which has been used to identify the neuronal cells, and calretinin which has been used as a marker of a subclass of horizontal, amacrine and ganglion cells.
Gene_expression (expressed) of MAP2 in ganglion cells associated with ganglion cysts
5) Confidence 0.65 Published 2010 Journal Acta Histochemica et Cytochemica Section Body Doc Link PMC3015049 Disease Relevance 0.51 Pain Relevance 0.03
Some cells expressed microtubule associated protein 2 (marker for mature neuron), or glial fibrillary acid protein (marker for glial cell).
Gene_expression (expressed) of microtubule associated protein 2 in glial cell
6) Confidence 0.65 Published 2010 Journal Acta Histochemica et Cytochemica Section Abstract Doc Link PMC3015049 Disease Relevance 0.09 Pain Relevance 0
To conclude, the present study demonstrated that the transplanted ADSCs survived and showed morphological and molecular differentiation with expressions of MAP2ab and GFAP.
Gene_expression (expressions) of MAP2ab
7) Confidence 0.65 Published 2010 Journal Acta Histochemica et Cytochemica Section Body Doc Link PMC3015049 Disease Relevance 0.17 Pain Relevance 0.03
It was observed that, although the transplanted ADSCs did not integrate into the other retinal cell layer, except in the GCL, the transplanted ADSCs morphologically differentiated and fully displayed an ability of differentiation into the various retinal cell types, thereby showing expressions of MAP2ab and GFAP.
Gene_expression (expressions) of MAP2ab
8) Confidence 0.65 Published 2010 Journal Acta Histochemica et Cytochemica Section Body Doc Link PMC3015049 Disease Relevance 0.29 Pain Relevance 0.04
In Figures 3A–F, the transplanted ADSC in the GCL expressed MAP2ab, while the transplanted ADSC in the vitreous chamber expressed MAP2ab in Figures 3G–I.
Gene_expression (expressed) of MAP2ab in vitreous chamber
9) Confidence 0.57 Published 2010 Journal Acta Histochemica et Cytochemica Section Body Doc Link PMC3015049 Disease Relevance 0.13 Pain Relevance 0
A subpopulation of the GFP immunoreactive cells was clearly found to co-express MAP2ab (microtubule-associated protein 2 which is found in mature neurons) and GFAP (glial fibrillary acid protein present in glial cells).
Gene_expression (found) of microtubule-associated protein 2 in glial cells
10) Confidence 0.57 Published 2010 Journal Acta Histochemica et Cytochemica Section Body Doc Link PMC3015049 Disease Relevance 0.08 Pain Relevance 0
A subpopulation of the GFP immunoreactive cells was clearly found to co-express MAP2ab (microtubule-associated protein 2 which is found in mature neurons) and GFAP (glial fibrillary acid protein present in glial cells).
Gene_expression (express) of MAP2ab in glial cells
11) Confidence 0.57 Published 2010 Journal Acta Histochemica et Cytochemica Section Body Doc Link PMC3015049 Disease Relevance 0.08 Pain Relevance 0
A subpopulation of the GFP immunoreactive cells was clearly found to co-express MAP2ab (microtubule-associated protein 2 which is found in mature neurons) and GFAP (glial fibrillary acid protein present in glial cells).
Gene_expression (express) of microtubule-associated protein 2 in glial cells
12) Confidence 0.57 Published 2010 Journal Acta Histochemica et Cytochemica Section Body Doc Link PMC3015049 Disease Relevance 0.08 Pain Relevance 0
Following the memory retention test, the levels of P-NF-H, MAP2, synaptophysin and myelin basic protein (MBP, a myelin marker) were measured in the brains of the mice by immunohistochemistry.
Gene_expression (levels) of MAP2 in brains
13) Confidence 0.49 Published 2008 Journal BMC Complement Altern Med Section Body Doc Link PMC2532680 Disease Relevance 0.26 Pain Relevance 0.14
Therefore, GFP-expressing Purkinje neurons isolated from transgenic mice were analysed after four weeks in culture, when, coincident with distinct axonal and dendritic morphologies, cultured Purkinje neurons exhibited dendrite-specific MAP2 expression characteristic of polarized neurons.
Gene_expression (expression) of MAP2 in neurons associated with targeted disruption
14) Confidence 0.46 Published 2007 Journal J. Neurochem. Section Abstract Doc Link 17448145 Disease Relevance 0.10 Pain Relevance 0.42
In this context it is of interest that we observed altered levels of the microtubule-associated proteins MAP2 and tau in spinal cord neurons of different dt alleles.
Gene_expression (levels) of MAP2 in spinal cord neurons associated with spinal cord
15) Confidence 0.45 Published 1998 Journal Mol. Cell. Neurosci. Section Abstract Doc Link 9604204 Disease Relevance 0.26 Pain Relevance 0.19
Expression levels of MAP2 were also decreased in all brain regions of A?
Gene_expression (Expression) of MAP2 in brain
16) Confidence 0.43 Published 2008 Journal BMC Complement Altern Med Section Body Doc Link PMC2532680 Disease Relevance 0.14 Pain Relevance 0.06
(25–35)-injected mice receiving vehicle compared to control mice, and administration of Kihi-to tended to increase MAP2 expression level in the dentate gyrus and cortex (Figures 4 and 7).
Gene_expression (expression) of MAP2 in dentate gyrus
17) Confidence 0.43 Published 2008 Journal BMC Complement Altern Med Section Body Doc Link PMC2532680 Disease Relevance 0.12 Pain Relevance 0.06
-syn accumulation, analysis of the dendritic marker MAP2 showed an increase in the percent area of the neuropil covered by dendrites in ?
Gene_expression (analysis) of MAP2 in neuropil
18) Confidence 0.42 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2824828 Disease Relevance 0.17 Pain Relevance 0.11
Interestingly, BV treatment reduced the number of microglial cells and astrocytes, and dramatically increased the expression of MAP2 in motor-related regions of the brainstem and spinal cord in comparison with age-matched hSOD1G93A control mice.
Gene_expression (expression) of MAP2 in spinal cord associated with medulla and spinal cord
19) Confidence 0.42 Published 2010 Journal J Neuroinflammation Section Body Doc Link PMC2974667 Disease Relevance 1.29 Pain Relevance 0.59
III tubulin or MAP2 expression (35.9%±13.0% at 10.7±2.0 DPI, n?
Gene_expression (expression) of MAP2 associated with infection
20) Confidence 0.42 Published 2010 Journal PLoS Biology Section Body Doc Link PMC2872647 Disease Relevance 0.33 Pain Relevance 0.13

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