INT75718

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Context Info
Confidence 0.32
First Reported 1998
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.31
Pain Relevance 0.62

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Cxadr) cell adhesion (Cxadr) mitochondrion organization (Cxadr)
plasma membrane (Cxadr) nucleus (Cxadr) protein complex (Cxadr)
Anatomy Link Frequency
neurons 1
parathyroid 1
Cxadr (Rattus norvegicus)
Pain Link Frequency Relevance Heat
qutenza 7 99.32 Very High Very High Very High
Calcitonin gene-related peptide 3 79.40 Quite High
Pain 3 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Parathyroid Cancer 3 91.92 High High
Necrosis 1 91.16 High High
Hyperplasia 26 72.24 Quite High
Apoptosis 3 40.44 Quite Low
Chronic Renal Failure 7 5.00 Very Low Very Low Very Low
Pruritus 4 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
Hypercalcemia 3 5.00 Very Low Very Low Very Low
Renal Disease 3 5.00 Very Low Very Low Very Low
Pyelonephritis 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These data support the hypothesis that Ca(2+)-induced relaxation is mediated by activation of the CaR associated with capsaicin-sensitive perivascular neurons.
Positive_regulation (activation) of CaR in neurons associated with qutenza
1) Confidence 0.32 Published 1998 Journal Am. J. Physiol. Section Abstract Doc Link 9612376 Disease Relevance 0 Pain Relevance 0.62
Furthermore, the response seen in iPTH after discontinuation and reintroduction of cinacalcet suggests that the remnant parathyroid tissue responded to stimulation of the CaR.
Positive_regulation (stimulation) of CaR in parathyroid
2) Confidence 0.02 Published 2009 Journal Nephrology Dialysis Transplantation Section Body Doc Link PMC2644631 Disease Relevance 0.31 Pain Relevance 0

General Comments

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