INT7576

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Context Info
Confidence 0.19
First Reported 1992
Last Reported 1992
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.30
Pain Relevance 0.62

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

aging (Nr3c1) intracellular (Nr3c1) DNA binding (Nr3c1)
protein complex (Nr3c1) cytoplasm (Nr3c1) cytosol (Nr3c1)
Anatomy Link Frequency
hippocampus 2
Nr3c1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
fluoxetine 3 99.72 Very High Very High Very High
Hippocampus 1 99.06 Very High Very High Very High
Locus ceruleus 1 85.20 High High
monoamine 1 80.64 Quite High
antagonist 1 79.04 Quite High
antidepressant 4 75.00 Quite High
depression 3 72.40 Quite High
Central nervous system 1 70.28 Quite High
Disease Link Frequency Relevance Heat
Depression 5 72.40 Quite High
Hyperphagia 1 53.68 Quite High
Sleep Disorders 1 53.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
No consistent change in steroid hormone receptor mRNA levels was seen in the hippocampus with the 3 drugs, but fluoxetine and idazoxan increased the level of mineralocorticoid receptor (MR) and glucocorticoid receptor (GR) mRNA, respectively, after 8 weeks of drug administration.
Positive_regulation (increased) of Transcription (level) of glucocorticoid receptor in hippocampus associated with hippocampus and fluoxetine
1) Confidence 0.19 Published 1992 Journal Brain Res. Section Abstract Doc Link 1351783 Disease Relevance 0.30 Pain Relevance 0.62

General Comments

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