INT7580

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Context Info
Confidence 0.70
First Reported 1984
Last Reported 2010
Negated 3
Speculated 1
Reported most in Abstract
Documents 54
Total Number 57
Disease Relevance 23.37
Pain Relevance 17.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Mbp)
Anatomy Link Frequency
CSF 7
blood 3
bands 3
urine 3
heart 2
Mbp (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Neuritis 27 99.90 Very High Very High Very High
Catecholamine 15 99.90 Very High Very High Very High
Dopamine 24 99.82 Very High Very High Very High
substance P 14 99.76 Very High Very High Very High
qutenza 14 99.42 Very High Very High Very High
Enkephalin 6 99.32 Very High Very High Very High
antagonist 20 98.84 Very High Very High Very High
ischemia 28 98.44 Very High Very High Very High
Angina 7 97.58 Very High Very High Very High
imagery 17 96.80 Very High Very High Very High
Disease Link Frequency Relevance Heat
Leukocytosis 4 100.00 Very High Very High Very High
Optic Neuritis 27 99.90 Very High Very High Very High
Recurrence 9 99.84 Very High Very High Very High
Hypotension 15 99.80 Very High Very High Very High
Death 4 99.80 Very High Very High Very High
Demyelinating Disease 58 99.48 Very High Very High Very High
Myocardial Infarction 2 99.08 Very High Very High Very High
Coronary Artery Disease 19 98.88 Very High Very High Very High
Middle Cerebral Artery Infarction 28 98.82 Very High Very High Very High
Disseminated Intravascular Coagulation 1 98.60 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Furthermore, we found no correlation between the rate of ramp increase in MBP and the sensitivity of the increase in ANA (r=0.24, P=0.29, n=22).
Positive_regulation (increase) of MBP
1) Confidence 0.70 Published 2008 Journal Neurosci. Lett. Section Abstract Doc Link 18948171 Disease Relevance 0.15 Pain Relevance 0.09
Similar elevations of mBP in baroreceptor-denervated rats were without effect.
Positive_regulation (elevations) of mBP
2) Confidence 0.69 Published 1984 Journal Brain Res. Section Abstract Doc Link 6733526 Disease Relevance 0 Pain Relevance 0.10
Corticosterone administration (1 mg.kg-1 day-1) restores MBP nearly to basal level.
Positive_regulation (restores) of MBP
3) Confidence 0.69 Published 1987 Journal Arch Mal Coeur Vaiss Section Abstract Doc Link 3116979 Disease Relevance 0 Pain Relevance 0.03
The cerebrospinal fluid (CSF) myelin basic protein (MBP) level was elevated and serum anti-myelin antibody was positive.
Positive_regulation (elevated) of myelin basic protein in CSF
4) Confidence 0.65 Published 1990 Journal Brain Dev. Section Abstract Doc Link 2092591 Disease Relevance 0.76 Pain Relevance 0.58
The cerebrospinal fluid (CSF) myelin basic protein (MBP) level was elevated and serum anti-myelin antibody was positive.
Positive_regulation (elevated) of MBP in CSF
5) Confidence 0.65 Published 1990 Journal Brain Dev. Section Abstract Doc Link 2092591 Disease Relevance 0.76 Pain Relevance 0.58
Intubation releases central and peripheral catecholamine and increases BIS, MBP, and HR [12,23].
Positive_regulation (increases) of MBP associated with catecholamine
6) Confidence 0.64 Published 2010 Journal Korean Journal of Anesthesiology Section Body Doc Link PMC2966706 Disease Relevance 0 Pain Relevance 0.53
Results show that low intensity stimulation at ventral sites evoked a significant increase of mBP (from 102 +/- 5.9 to 127 +/- 8.6 mmHg, n = 10, p < 0.0001) with little changes of BlP (from 12 +/- 2.2 to 16 +/- 2.9 cmH(2)O, n = 10, p < 0.0005), whilst at more dorsal sites significant increases of BlP were elicited (from 12 +/- 8.3 to 38 +/- 4.6 cmH(2)O,n = 10, p < 0.0001) with only a small rise of mBP (from 102 +/- 6.2 to 111 +/- 9.8 mmHg, n = 10, p < 0.005).
Positive_regulation (increase) of mBP in dorsal
7) Confidence 0.62 Published 2004 Journal Clin. Auton. Res. Section Abstract Doc Link 15316845 Disease Relevance 0.14 Pain Relevance 0.10
Electrical stimulation of the lower thoracic region (T9-12) via a pithing rod produced a frequency (1-8 Hz)-dependent fall in elevated MBP.
Positive_regulation (elevated) of MBP in thoracic region
8) Confidence 0.60 Published 1992 Journal Brain Res. Section Abstract Doc Link 1351787 Disease Relevance 0 Pain Relevance 0.54
Injection of L-glu decreased the duration of inspiration (Ti) and Te and increased MBP.
Positive_regulation (increased) of MBP
9) Confidence 0.59 Published 1994 Journal Hua Xi Yi Ke Da Xue Xue Bao Section Abstract Doc Link 7896242 Disease Relevance 0 Pain Relevance 0.41
Noradrenaline in doses ranging from 0.03 to 0.3 micrograms (i.t.) did not alter the mean blood pressure (MBP) while higher doses (1, 3 and 10 micrograms, i.t.) caused a dose-dependent increase in MBP.
Positive_regulation (increase) of MBP in blood associated with noradrenaline
10) Confidence 0.57 Published 1996 Journal J. Auton. Nerv. Syst. Section Abstract Doc Link 8816361 Disease Relevance 0.25 Pain Relevance 0.28
Intubation increased MBP in controls, but the MBP at 1 or 2 min after intubation (L1, 2) in nimodipine or nicardipine group was similar to before anesthetic induction (P < 0.05 compared to control group) (Table 3).
Positive_regulation (increased) of MBP
11) Confidence 0.56 Published 2010 Journal Korean Journal of Anesthesiology Section Body Doc Link PMC2966706 Disease Relevance 0.07 Pain Relevance 0.14
Examination of cerebrospinal fluid revealed elevation of mononuclear cells and myelin basic protein (MBP).
Positive_regulation (elevation) of myelin basic protein in mononuclear cells
12) Confidence 0.47 Published 1999 Journal Rinsho Shinkeigaku Section Abstract Doc Link 10586626 Disease Relevance 0.99 Pain Relevance 0.14
Examination of cerebrospinal fluid revealed elevation of mononuclear cells and myelin basic protein (MBP).
Positive_regulation (elevation) of MBP in mononuclear cells
13) Confidence 0.47 Published 1999 Journal Rinsho Shinkeigaku Section Abstract Doc Link 10586626 Disease Relevance 0.99 Pain Relevance 0.14
The cerebrospinal fluid revealed elevated myelin basic protein.
Positive_regulation (elevated) of myelin basic protein in cerebrospinal fluid
14) Confidence 0.45 Published 2006 Journal J. Neurol. Section Abstract Doc Link 16502219 Disease Relevance 0.62 Pain Relevance 0.20
Confirmation experiments verified that stimulation with beta-endorphin increased the mRNA levels of myelin basic protein, glutathione S-transferase pi, c-junD and rab16 (P < 0.05), genes that are associated with oligodendrogenesis.
Positive_regulation (increased) of myelin basic protein
15) Confidence 0.45 Published 2006 Journal Eur. J. Neurosci. Section Abstract Doc Link 16706836 Disease Relevance 0 Pain Relevance 0.50
Results show that low intensity stimulation at ventral sites evoked a significant increase of mBP (from 102 +/- 5.9 to 127 +/- 8.6 mmHg, n = 10, p < 0.0001) with little changes of BlP (from 12 +/- 2.2 to 16 +/- 2.9 cmH(2)O, n = 10, p < 0.0005), whilst at more dorsal sites significant increases of BlP were elicited (from 12 +/- 8.3 to 38 +/- 4.6 cmH(2)O,n = 10, p < 0.0001) with only a small rise of mBP (from 102 +/- 6.2 to 111 +/- 9.8 mmHg, n = 10, p < 0.005).
Positive_regulation (rise) of mBP in dorsal
16) Confidence 0.45 Published 2004 Journal Clin. Auton. Res. Section Abstract Doc Link 15316845 Disease Relevance 0.13 Pain Relevance 0.12
After MBP was restored to 94 +/- 3 mmHg using volume repletion, HR increased to 95 +/- 3 beats/min (P less than 0.001).
Positive_regulation (restored) of MBP
17) Confidence 0.45 Published 1986 Journal Acta Anaesthesiol Scand Section Abstract Doc Link 3811794 Disease Relevance 0.40 Pain Relevance 0.07
Changes in resting MBP and HR after administration of phenylephrine were observed from 15 min to 105 min.
Positive_regulation (resting) of MBP
18) Confidence 0.44 Published 2010 Journal Biopsychosoc Med Section Body Doc Link PMC2967492 Disease Relevance 0 Pain Relevance 0.05
Mucosal application of capsaicin (0.03 - 1 mg/ml for 10 min) increased GMBF in a concentration-dependent manner, without any change in PD, pH and MBP.
Positive_regulation (increased) of MBP associated with qutenza
19) Confidence 0.44 Published 1991 Journal Jpn. J. Pharmacol. Section Abstract Doc Link 1812299 Disease Relevance 0 Pain Relevance 0.61
Peripherally administered nicardipine or nimodipine blocked the increase in MBP associated with endotracheal intubation, but failed to block the increase in BIS, implying little indirect action on BIS through affecting hemodynamics or blocking movement of peripheral catecholamine.
Positive_regulation (increase) of MBP associated with catecholamine
20) Confidence 0.43 Published 2010 Journal Korean Journal of Anesthesiology Section Body Doc Link PMC2966706 Disease Relevance 0 Pain Relevance 0.55

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