INT75935

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.18
First Reported 1998
Last Reported 2009
Negated 1
Speculated 0
Reported most in Abstract
Documents 4
Total Number 4
Disease Relevance 3.82
Pain Relevance 1.70

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (MLXIPL) nucleoplasm (MLXIPL) small molecule metabolic process (MLXIPL)
nucleus (MLXIPL) DNA binding (MLXIPL) transcription factor binding (MLXIPL)
Anatomy Link Frequency
TMJ 1
bone marrow 1
MLXIPL (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 10 99.92 Very High Very High Very High
Dopamine 1 99.40 Very High Very High Very High
Kappa opioid receptor 3 99.22 Very High Very High Very High
Snapping jaw 10 97.88 Very High Very High Very High
Opioid 7 79.28 Quite High
cytokine 4 75.00 Quite High
opioid receptor 1 75.00 Quite High
Dynorphin 1 39.24 Quite Low
Calcium channel 6 5.00 Very Low Very Low Very Low
Angina 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pain 10 99.92 Very High Very High Very High
Adhesions 29 99.50 Very High Very High Very High
Temporomandibular Joint Syndrome 10 97.88 Very High Very High Very High
Hypertension 69 92.52 High High
Lewis Lung Carcinoma 4 84.16 Quite High
Cancer 7 81.96 Quite High
Apoptosis 1 27.76 Quite Low
Diabetes Mellitus 13 5.00 Very Low Very Low Very Low
Obesity 11 5.00 Very Low Very Low Very Low
Disease 11 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In conclusion, our results indicate that the presence of FA or a postoperative worsening of FA (including postoperative new FA formation) seems not to affect the clinical outcome as regards MIO and VAS in patients with chronic closed lock of the TMJ.
Neg (not) Regulation (affect) of MIO in TMJ associated with pain, snapping jaw and adhesions
1) Confidence 0.18 Published 2005 Journal Int J Oral Maxillofac Surg Section Abstract Doc Link 15982854 Disease Relevance 1.49 Pain Relevance 0.59
In each group, the changes of the MIO, VAS and severity of FA (FA score) after the first VGIR were studied.
Regulation (changes) of MIO associated with pain and adhesions
2) Confidence 0.18 Published 2005 Journal Int J Oral Maxillofac Surg Section Abstract Doc Link 15982854 Disease Relevance 1.51 Pain Relevance 0.70
A recent study [31] that used this approach on the Wellcome Trust data observed some interesting findings including pathways involved in dopamine signaling, PKA signaling and ChREBP regulation.
Regulation (regulation) of ChREBP associated with dopamine
3) Confidence 0.06 Published 2009 Journal PLoS Genetics Section Body Doc Link PMC2702100 Disease Relevance 0.17 Pain Relevance 0.05
In conclusion, the affinity state of the kappa-opioid receptors in stromal bone marrow cells seems to modulate the hematopoietic effect of melatonin and/or MIO15.
Regulation (modulate) of MIO15 in bone marrow associated with kappa opioid receptor
4) Confidence 0.00 Published 1998 Journal Ann. N. Y. Acad. Sci. Section Abstract Doc Link 9629267 Disease Relevance 0.65 Pain Relevance 0.37

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox