INT76001

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Context Info
Confidence 0.16
First Reported 1998
Last Reported 1998
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.93
Pain Relevance 1.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Ngf, Ngfr) cell differentiation (Ngfr) nuclear envelope (Ngfr)
aging (Ngf) Golgi apparatus (Ngfr) cytoplasm (Ngfr)
Anatomy Link Frequency
central nervous system 1
Ngf (Rattus norvegicus)
Ngfr (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Nerve growth factor 14 100.00 Very High Very High Very High
Central nervous system 2 98.84 Very High Very High Very High
Inflammation 4 98.44 Very High Very High Very High
Pain 4 97.76 Very High Very High Very High
Peripheral nervous system 2 91.44 High High
Disease Link Frequency Relevance Heat
INFLAMMATION 2 98.44 Very High Very High Very High
Pain 2 97.76 Very High Very High Very High
Necrosis 2 97.76 Very High Very High Very High
Cancer 2 97.40 Very High Very High Very High
Apoptosis 2 88.68 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Finally, NGF recently was shown to activate the neurotrophin receptor p75 (p75NTR), a receptor with no intrinsic catalytic activity and with similarities to members of the tumor necrosis factor receptor family.
NGF Positive_regulation (activate) of p75NTR associated with necrosis, nerve growth factor and cancer
1) Confidence 0.16 Published 1998 Journal Bioessays Section Abstract Doc Link 9631659 Disease Relevance 0.48 Pain Relevance 0.53
During normal development, the activation of p75NTR by NGF actually kills cells in the central nervous system.
NGF Positive_regulation (activation) of p75NTR in central nervous system associated with nerve growth factor and central nervous system
2) Confidence 0.16 Published 1998 Journal Bioessays Section Abstract Doc Link 9631659 Disease Relevance 0.45 Pain Relevance 0.52

General Comments

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