INT76026

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Context Info
Confidence 0.28
First Reported 1998
Last Reported 1998
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.42
Pain Relevance 0.64

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

oxidoreductase activity (Cyp2e1, Cyp3a11) endoplasmic reticulum (Cyp2e1, Cyp3a11) mitochondrion (Cyp2e1)
enzyme binding (Cyp2e1)
Cyp2e1 (Mus musculus)
Cyp3a11 (Mus musculus)
Pain Link Frequency Relevance Heat
Paracetamol 8 100.00 Very High Very High Very High
alcohol 5 100.00 Very High Very High Very High
Disease Link Frequency Relevance Heat
Toxicity 1 98.68 Very High Very High Very High
Hepatotoxicity 7 95.28 Very High Very High Very High
Targeted Disruption 1 46.40 Quite Low
Sprains And Strains 1 25.68 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, CYP3A, which is also induced by alcohol, has been shown to have a greater affinity for acetaminophen than CYP2E.
CYP2E Binding (affinity) of CYP3A associated with paracetamol and alcohol
1) Confidence 0.28 Published 1998 Journal Biochem. Pharmacol. Section Abstract Doc Link 9633991 Disease Relevance 0.42 Pain Relevance 0.64

General Comments

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