INT76084

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Context Info
Confidence 0.08
First Reported 1998
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.84
Pain Relevance 0.71

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
ECs 4
ecs (Mus musculus)
Pain Link Frequency Relevance Heat
Morphine 7 96.76 Very High Very High Very High
chemokine 7 93.44 High High
adenocard 1 87.36 High High
Inflammation 39 72.64 Quite High
cytokine 13 69.64 Quite High
agonist 1 54.48 Quite High
Inflammatory marker 3 5.00 Very Low Very Low Very Low
isoflurane 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adhesions 3 100.00 Very High Very High Very High
Hyperglycemia 2 94.84 High High
Hyperlipidemia 1 94.12 High High
Insulin Resistance 38 92.96 High High
Diabetes Mellitus 11 91.64 High High
Obesity 63 78.80 Quite High
Targeted Disruption 40 73.44 Quite High
INFLAMMATION 43 72.64 Quite High
Increased Venous Pressure Under Development 1 25.00 Low Low
Atherosclerosis 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In these model conditions, activated 12/15LO regulates monocyte attachment to ECs in part by increasing expression of adhesion molecule ICAM-1 on the surface of ECs via activation of RhoA and NF-?
Positive_regulation (increasing) of Positive_regulation (surface) of ECs in ECs associated with adhesions
1) Confidence 0.08 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2746280 Disease Relevance 1.84 Pain Relevance 0.24
These data suggest that cAMP is required for the induction of iNOS in ECs and that NO may directly impair adenylate cyclase activity, preventing iNOS activation.
Positive_regulation (required) of Positive_regulation (induction) of ECs in ECs
2) Confidence 0.01 Published 1998 Journal J. Cardiovasc. Pharmacol. Section Abstract Doc Link 9641464 Disease Relevance 0 Pain Relevance 0.48

General Comments

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