INT76089

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Context Info
Confidence 0.27
First Reported 1998
Last Reported 1998
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.05
Pain Relevance 0.65

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

isomerase activity (ISYNA1) cytoplasm (ISYNA1)
Anatomy Link Frequency
ECs 2
IFNA1 (Homo sapiens)
ISYNA1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Morphine 7 97.52 Very High Very High Very High
agonist 1 79.36 Quite High
adenocard 1 78.40 Quite High
Inflammation 1 54.80 Quite High
Disease Link Frequency Relevance Heat
INFLAMMATION 1 54.80 Quite High
Increased Venous Pressure Under Development 1 45.04 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Exposure of ECs to the NO donor, SNAP, before the addition of LPS + IFN, blocked iNOS induction, whereas preincubation of ECs with inhibitors of NOS, before morphine or anandamide exposure, restored LPS + IFN induction of iNOS, suggesting a direct impact of NO on the regulation of iNOS activity.
IFN Negative_regulation (blocked) of Positive_regulation (induction) of iNOS in ECs associated with morphine
1) Confidence 0.27 Published 1998 Journal J. Cardiovasc. Pharmacol. Section Abstract Doc Link 9641464 Disease Relevance 0.05 Pain Relevance 0.65

General Comments

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