INT76159

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Context Info
Confidence 0.65
First Reported 1998
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 5
Total Number 6
Disease Relevance 5.12
Pain Relevance 0.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (CEACAM1) plasma membrane (CEACAM1) molecular_function (CEACAM1)
Anatomy Link Frequency
platelet 2
lamina 1
parathyroid 1
T cell 1
CEACAM1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 66 94.36 High High
Pain 1 70.24 Quite High
agonist 18 53.20 Quite High
cytokine 11 5.00 Very Low Very Low Very Low
Inflammatory response 7 5.00 Very Low Very Low Very Low
withdrawal 4 5.00 Very Low Very Low Very Low
Inflammatory mediators 4 5.00 Very Low Very Low Very Low
spastic colon 2 5.00 Very Low Very Low Very Low
Angina 2 5.00 Very Low Very Low Very Low
abdominal pain 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adhesions 13 100.00 Very High Very High Very High
Crohn's Disease 218 99.84 Very High Very High Very High
Cirrhosis 4 98.12 Very High Very High Very High
Phosphate Metabolism Disorders 10 97.80 Very High Very High Very High
Inflammatory Bowel Disease 156 95.68 Very High Very High Very High
INFLAMMATION 71 94.36 High High
Influenza Virus Infection 23 92.00 High High
Gastrointestinal Disease 2 91.68 High High
Infection 45 90.80 High High
Chronic Hepatitis 2 90.72 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Similarly, platelet-neutrophil aggregates were detected by simultaneous incubation with mouse anti-human CD42b:RPE-Cy5 and mouse IgM anti-human CD66:FITC (1?
Gene_expression (anti) of CD66 in platelet
1) Confidence 0.65 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2735777 Disease Relevance 0 Pain Relevance 0
10, Dako), mouse anti-human CD42b:RPE-Cy5 and mouse anti-human CD38:RPE or mouse anti-human CD66:RPE.
Gene_expression (anti) of CD66
2) Confidence 0.65 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2735777 Disease Relevance 0.17 Pain Relevance 0.03
Serum levels of osteocalcin (BGP) and parathyroid hormone (PTH) in patients of hepatic cirrhosis without osteodystrophy were lower than those with osteodystrophy.
Gene_expression (levels) of BGP in parathyroid associated with phosphate metabolism disorders and cirrhosis
3) Confidence 0.58 Published 1998 Journal Nippon Rinsho Section Abstract Doc Link 9648489 Disease Relevance 1.77 Pain Relevance 0.07
Finally, within this gene category, expression of CEACAM1 (a known neutrophil activation marker and regulator of T cell function [34,35]) was examined by immunohistochemistry.
Spec (examined) Gene_expression (expression) of CEACAM1 in T cell
4) Confidence 0.49 Published 2005 Journal PLoS Medicine Section Body Doc Link PMC1188246 Disease Relevance 1.07 Pain Relevance 0.08
Infiltrating immune cells in the lamina propria were stained by anti-CEACAM1 antibody in CD, but not in UC, suggesting that CEACAM1 may be a better therapeutic target in CD.
Gene_expression (antibody) of CEACAM1 in lamina associated with crohn's disease
5) Confidence 0.43 Published 2005 Journal PLoS Medicine Section Body Doc Link PMC1188246 Disease Relevance 1.20 Pain Relevance 0.07
More recently, it was shown that URT viruses can induce up-regulated expression of carcinoembryonic antigen-related cell adhesion molecule 1, ICAM1, and platelet-activating receptor, additional eukaryotic receptors known to be used for adherence by multiple human mucosal pathogens [242526].
Gene_expression (expression) of antigen-related cell adhesion molecule 1 in platelet associated with adhesions
6) Confidence 0.08 Published 2010 Journal J Leukoc Biol Section Body Doc Link PMC2812561 Disease Relevance 0.90 Pain Relevance 0

General Comments

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