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Context Info
Confidence 0.02
First Reported 1998
Last Reported 1998
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.08
Pain Relevance 1.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Prkaca) Golgi apparatus (Prkaca) protein complex (Prkaca)
signal transducer activity (Oprm1) cytoplasm (Prkaca) nucleus (Prkaca)
Prkaca (Mus musculus)
Oprm1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
agonist 4 99.44 Very High Very High Very High
Opioid 1 99.36 Very High Very High Very High
Morphine 3 98.34 Very High Very High Very High
Enkephalin 6 97.32 Very High Very High Very High
narcan 1 89.92 High High
antagonist 1 89.56 High High
MU agonist 1 83.40 Quite High
opioid receptor 2 77.68 Quite High
Disease Link Frequency Relevance Heat
Neuroblastoma 1 82.20 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Although morphine and related alkaloids as well as some peptide agonists (PLO17 and beta-endorphin) stimulated phosphorylation of MOR-1 by PKA, the potent mu-opioid-selective peptide [D-Ala2,N-MePhe4,Gly-ol5]-enkephalin (DAMGO) or other enkephalin analogues such as [D-Ala2]-Met5-enkephalinamide (DALA), [D-Ala2,D-Leu5]-enkephalin (DADLE), and Met5-enkephalin had no effect.
PKA Positive_regulation (stimulated) of Phosphorylation (phosphorylation) of MOR-1 associated with agonist, enkephalin, opioid and morphine
1) Confidence 0.02 Published 1998 Journal J. Neurochem. Section Abstract Doc Link 9648870 Disease Relevance 0.08 Pain Relevance 1.22

General Comments

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