INT76196

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Context Info
Confidence 0.06
First Reported 1998
Last Reported 1998
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

translation factor activity, nucleic acid binding (EIF2B3) cytoplasm (EIF2B3) signal transducer activity (HTR1A)
cytosol (EIF2B3) plasma membrane (HTR1A) biosynthetic process (EIF2B3)
Anatomy Link Frequency
HeLa 2
HTR1A (Homo sapiens)
EIF2B3 (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 14 100.00 Very High Very High Very High
Sumatriptan 2 46.48 Quite Low
Potency 4 25.00 Low Low

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the present study, the intrinsic activity of a series of 5-HT1B/D ligands was investigated at human 5-HT1A (h 5-HT1A) receptors by measuring G-protein activation in recombinant C6-glial and HeLa membranes, using agonist-stimulated [35S]GTPgammaS binding.
5-HT1A Binding (binding) of GTPgammaS in HeLa associated with agonist
1) Confidence 0.06 Published 1998 Journal Naunyn Schmiedebergs Arch. Pharmacol. Section Abstract Doc Link 9650800 Disease Relevance 0 Pain Relevance 0.08
In the present study, the intrinsic activity of a series of 5-HT1B/D ligands was investigated at human 5-HT1A (h 5-HT1A) receptors by measuring G-protein activation in recombinant C6-glial and HeLa membranes, using agonist-stimulated [35S]GTPgammaS binding.
5-HT1A Binding (binding) of GTPgammaS in HeLa associated with agonist
2) Confidence 0.06 Published 1998 Journal Naunyn Schmiedebergs Arch. Pharmacol. Section Abstract Doc Link 9650800 Disease Relevance 0 Pain Relevance 0.08

General Comments

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