INT764

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Context Info
Confidence 0.67
First Reported 1976
Last Reported 2010
Negated 12
Speculated 0
Reported most in Abstract
Documents 25
Total Number 26
Disease Relevance 25.58
Pain Relevance 8.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

biosynthetic process (OLAH)
Anatomy Link Frequency
nodules 3
joints 2
synovial fluid 1
TMJ 1
leukocyte 1
OLAH (Homo sapiens)
Pain Link Frequency Relevance Heat
Arthritis 34 99.96 Very High Very High Very High
cytokine 4 99.96 Very High Very High Very High
rheumatoid arthritis 93 99.92 Very High Very High Very High
Inflammation 17 99.92 Very High Very High Very High
Inflammatory response 1 99.80 Very High Very High Very High
cINOD 14 99.56 Very High Very High Very High
backache 4 99.24 Very High Very High Very High
Pain 20 98.80 Very High Very High Very High
corticosteroid 6 98.16 Very High Very High Very High
Inflammatory marker 4 97.64 Very High Very High Very High
Disease Link Frequency Relevance Heat
Arthritis 38 99.96 Very High Very High Very High
Rheumatoid Arthritis 105 99.92 Very High Very High Very High
INFLAMMATION 31 99.92 Very High Very High Very High
Ankylosis 1 99.92 Very High Very High Very High
Arthropathy 7 99.90 Very High Very High Very High
Disease 28 99.82 Very High Very High Very High
Low Back Pain 21 99.40 Very High Very High Very High
Osteolysis 1 99.36 Very High Very High Very High
Pressure And Volume Under Development 36 99.12 Very High Very High Very High
Rheumatoid Vasculitis 20 99.10 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
He was seronegative for rheumatoid factor and no radiologically evident erosion was noted in the joints of his hands and feet.
Gene_expression (seronegative) of rheumatoid factor in joints
1) Confidence 0.67 Published 1999 Journal J. Formos. Med. Assoc. Section Abstract Doc Link 10463003 Disease Relevance 0.89 Pain Relevance 0.12
Serological tests including rheumatoid factor, antinuclear antibody, and human leukocyte antigen B27 were all negative.
Neg (negative) Gene_expression (negative) of rheumatoid factor in leukocyte
2) Confidence 0.64 Published 2004 Journal Rheumatol. Int. Section Abstract Doc Link 14593491 Disease Relevance 0.73 Pain Relevance 0.15
The rheumatoid factor and HLA B 27 antigen were absent.
Neg (absent) Gene_expression (absent) of rheumatoid factor
3) Confidence 0.59 Published 1999 Journal J Clin Rheumatol Section Abstract Doc Link 19078345 Disease Relevance 0.90 Pain Relevance 0.20
Rheumatoid factor in serum was always negative, and the patient has also an iridocyclitis.
Neg (negative) Gene_expression (negative) of Rheumatoid factor associated with iridocyclitis
4) Confidence 0.59 Published 1996 Journal Reumatizam Section Abstract Doc Link 9213882 Disease Relevance 0.52 Pain Relevance 0.25
Rheumatoid factor and antinuclear antibodies were negative.
Neg (negative) Gene_expression (negative) of Rheumatoid factor
5) Confidence 0.53 Published 2007 Journal Gerontology Section Abstract Doc Link 17510560 Disease Relevance 1.16 Pain Relevance 0.29
Measurements of rheumatoid arthritis must include not only conventional indices of disease activity (pain, morning stiffness, articular index, swelling) but also extra-articular features such as nodules, E.S.R., and rheumatoid factor titre.
Gene_expression (nodules) of rheumatoid factor in nodules associated with pain, pressure and volume under development, rheumatoid arthritis and disease
6) Confidence 0.50 Published 1977 Journal Agents Actions Suppl. Section Abstract Doc Link 272833 Disease Relevance 0.47 Pain Relevance 0.19
RA patients possessing the B27 antigen did not differ regarding the age of the onset of disease, the distribution of affected joints during the follow-up (3-10 years), the development stages of the disease and the presence of rheumatoid factor when compared with B27 negative RA patients.
Gene_expression (presence) of rheumatoid factor in joints associated with rheumatoid arthritis and disease
7) Confidence 0.50 Published 1991 Journal Acta Med Iugosl Section Abstract Doc Link 1950638 Disease Relevance 1.14 Pain Relevance 0.38
Rheumatoid factor is usually absent, and the prognosis appears to be better than that for rheumatoid arthritis.
Neg (absent) Gene_expression (absent) of Rheumatoid factor associated with rheumatoid arthritis
8) Confidence 0.48 Published 1977 Journal Postgrad Med Section Abstract Doc Link 834678 Disease Relevance 0.81 Pain Relevance 0.33
Both cases were complicated by silicosis and the laboratory findings showed high serum levels of P-ANCA, ANA and rheumatoid factor and inflammatory responses, indicating they were suspected vasculitis.
Gene_expression (levels) of rheumatoid factor associated with inflammatory response, increased venous pressure under development and occupational lung diseases
9) Confidence 0.07 Published 1999 Journal Ryumachi Section Abstract Doc Link 10695408 Disease Relevance 2.08 Pain Relevance 0.26
Rheumatoid factor is present in about 80 percent of patients with rheumatoid arthritis but is not specific for this diagnosis.
Gene_expression (present) of Rheumatoid factor associated with rheumatoid arthritis
10) Confidence 0.07 Published 1988 Journal Am. J. Med. Section Abstract Doc Link 3263044 Disease Relevance 1.27 Pain Relevance 0.37
Rheumatoid factor (RF), anti-citrullinated peptide antibodies (ACPA), anti-nuclear antibodies (ANA), and anti-neutrophil cytoplasmic antibodies (ANCA) were all tested negative.
Neg (negative) Gene_expression (tested) of Rheumatoid factor in neutrophil
11) Confidence 0.06 Published 2010 Journal BMC Infect Dis Section Body Doc Link PMC2931510 Disease Relevance 1.04 Pain Relevance 0.07
Since rheumatoid factor is mainly produced locally in the inflamed synovial membranes, our results suggest an effect of piroxicam on the immune system locally but not in the peripheral blood.
Gene_expression (produced) of rheumatoid factor in immune system
12) Confidence 0.06 Published 1984 Journal Inflammation Section Abstract Doc Link 6480068 Disease Relevance 0.31 Pain Relevance 0.15
In hindsight, the diagnosis of rheumatoid vasculitis appeared unlikely in our patient due to the absence of rheumatoid factor, which is usually highly elevated in patients with RV [22,23].
Neg (absence) Gene_expression (absence) of rheumatoid factor associated with rheumatoid vasculitis
13) Confidence 0.06 Published 2010 Journal BMC Infect Dis Section Body Doc Link PMC2931510 Disease Relevance 1.73 Pain Relevance 0.20
Rheumatoid factor was detected in serum and in synovial fluid.
Gene_expression (detected) of Rheumatoid factor in synovial fluid
14) Confidence 0.05 Published 1979 Journal Acta Med. Austriaca Section Abstract Doc Link 94968 Disease Relevance 1.06 Pain Relevance 0.65
However the presence of rheumatoid factor, histologically classic rheumatoid nodules, and the histocompatibility cell wall antigen (HLA-B27) helps distinguish one from the other.
Gene_expression (presence) of rheumatoid factor in nodules associated with rheumatoid arthritis
15) Confidence 0.04 Published 1976 Journal Arthritis Rheum. Section Abstract Doc Link 1252261 Disease Relevance 0.44 Pain Relevance 0.38
Lung involvement in rheumatoid factor-negative arthritis.
Neg (negative) Gene_expression (negative) of rheumatoid factor in Lung associated with arthritis
16) Confidence 0.04 Published 1993 Journal Scand. J. Rheumatol. Section Title Doc Link 8235492 Disease Relevance 1.68 Pain Relevance 0.58
Rheumatoid factor, CCP antibodies, ANA, and HLA-B27 were negative and/or normal.
Neg (negative) Gene_expression (negative) of Rheumatoid factor
17) Confidence 0.04 Published 2010 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2902413 Disease Relevance 1.14 Pain Relevance 0.35
In patients with rheumatoid arthritis treated with piroxicam, there are no overall changes in lymphocyte numbers or T4/T8 ratios, but numbers of activated cells expressing la decrease and rheumatoid factor titers may also fall.
Gene_expression (expressing) of rheumatoid factor in lymphocyte associated with rheumatoid arthritis
18) Confidence 0.04 Published 1984 Journal Am. J. Med. Section Abstract Doc Link 6238529 Disease Relevance 0.42 Pain Relevance 0.37
The precise role of B cells in RA has not been elucidated, but potential mechanisms include an antigen-presenting function, secretion of proinflammatory cytokines, production of rheumatoid factor, and costimulation of T cells [2,3].
Gene_expression (production) of rheumatoid factor in B cells associated with rheumatoid arthritis and cytokine
19) Confidence 0.03 Published 2003 Journal Arthritis Res Ther Section Body Doc Link PMC2833440 Disease Relevance 1.05 Pain Relevance 0.34
Autoantibody screen and rheumatoid factor were negative.
Neg (negative) Gene_expression (negative) of rheumatoid factor
20) Confidence 0.03 Published 2008 Journal Cases J Section Body Doc Link PMC2543002 Disease Relevance 1.47 Pain Relevance 0.18

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