INT76404

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Context Info
Confidence 0.68
First Reported 1998
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 5
Disease Relevance 0.87
Pain Relevance 0.68

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Cnp) plasma membrane (Cnp) intracellular (Cnp)
cytoplasm (Cnp)
Anatomy Link Frequency
spinal cord 1
paw 1
corpus callosum 1
striatum 1
ventral 1
Cnp (Rattus norvegicus)
Pain Link Frequency Relevance Heat
substantia gelatinosa 6 96.64 Very High Very High Very High
Dorsal horn 34 96.44 Very High Very High Very High
Pain 1 96.20 Very High Very High Very High
Spinal cord 46 95.68 Very High Very High Very High
qutenza 112 89.56 High High
Sciatic nerve 4 80.08 Quite High
dorsal root ganglion 22 70.08 Quite High
unmyelinated 32 50.00 Quite Low
imagery 4 30.60 Quite Low
superficial lamina 4 28.40 Quite Low
Disease Link Frequency Relevance Heat
Pressure And Volume Under Development 5 100.00 Very High Very High Very High
Natriuresis 5 99.80 Very High Very High Very High
Erythema 1 96.72 Very High Very High Very High
Pain 1 96.20 Very High Very High Very High
Volume Depletion And Dehydration 2 71.88 Quite High
Ganglion Cysts 22 69.12 Quite High
Stroke 80 50.00 Quite Low
Nociception 8 36.80 Quite Low
Middle Cerebral Artery Infarction 28 5.00 Very Low Very Low Very Low
Cv Unclassified Under Development 14 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
For quantification of axons and myelinating oligodendrocytes, NF-H, CNPase, MBP, and Bielschowsky and Luxol fast blue positive areas were digitized throughout the peri-infarct corpus callosum and striatum, as well as the contralateral homologous area.
Localization (digitized) of CNPase in striatum
1) Confidence 0.68 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2884017 Disease Relevance 0 Pain Relevance 0
For quantification of axons and myelinating oligodendrocytes, NF-H, CNPase, MBP, and Bielschowsky and Luxol fast blue positive areas were digitized throughout the peri-infarct corpus callosum and striatum, as well as the contralateral homologous area.
Localization (digitized) of CNPase in corpus callosum
2) Confidence 0.23 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2884017 Disease Relevance 0 Pain Relevance 0
This was confirmed using confocal microscopy, which revealed minimal colocalization between SSeCKS and CNPase except for the occasional double-labeled puncta observed in laminae ventral to the substantia gelatinosa.
Localization (colocalization) of CNPase in ventral associated with substantia gelatinosa
3) Confidence 0.21 Published 2008 Journal J Brachial Plex Peripher Nerve Inj Section Body Doc Link PMC2277419 Disease Relevance 0.14 Pain Relevance 0.13
Evaluation of colocalization between SSeCKS and CNPase at both the fluorescence and confocal microscope level suggests myelinated axons in the dorsal horn of the spinal cord contain minimal SSeCKS-IR.
Localization (colocalization) of CNPase in spinal cord associated with dorsal horn and spinal cord
4) Confidence 0.09 Published 2008 Journal J Brachial Plex Peripher Nerve Inj Section Body Doc Link PMC2277419 Disease Relevance 0 Pain Relevance 0.46
We have found that both ovCNP-39 and the endogenous C-type natriuretic peptide, CNP-22, produce oedema in the rat paw and release histamine from rat peritoneal mast cells.
Localization (release) of CNP-22 in paw associated with natriuresis and pressure and volume under development
5) Confidence 0.02 Published 1998 Journal Toxicon Section Abstract Doc Link 9663691 Disease Relevance 0.73 Pain Relevance 0.10

General Comments

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