INT76477

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Context Info
Confidence 0.50
First Reported 1998
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 14
Total Number 14
Disease Relevance 14.77
Pain Relevance 1.42

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (CD99) plasma membrane (CD99) cytoplasm (CD99)
Anatomy Link Frequency
smooth muscle 2
CD99 (Homo sapiens)
Pain Link Frequency Relevance Heat
imagery 17 89.32 High High
backache 1 87.84 High High
Pain 10 87.04 High High
abdominal pain 3 86.16 High High
Snapping jaw 1 85.12 High High
cva 7 84.16 Quite High
headache 8 80.40 Quite High
positron emission tomography 8 75.60 Quite High
antagonist 1 58.32 Quite High
Angina 5 57.60 Quite High
Disease Link Frequency Relevance Heat
Synovial Sarcoma 17 99.80 Very High Very High Very High
Cancer 209 99.56 Very High Very High Very High
Neuroendocrine Cancer 2 99.32 Very High Very High Very High
Precursor Cell Lymphoblastic Leukemia-lymphoma 6 99.22 Very High Very High Very High
Primitive Neuroectodermal Tumors 39 98.72 Very High Very High Very High
Sarcoma 47 98.62 Very High Very High Very High
Hemangiopericytoma 7 98.08 Very High Very High Very High
Mesothelioma 79 96.72 Very High Very High Very High
Metastasis 13 95.52 Very High Very High Very High
Malignant Neoplastic Disease 27 94.96 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Immunohistochemical staining showed the cells were positive for MIC-2 (CD99).
Positive_regulation (positive) of CD99
1) Confidence 0.50 Published 2008 Journal Neurol. Med. Chir. (Tokyo) Section Abstract Doc Link 18296876 Disease Relevance 1.19 Pain Relevance 0.25
Immunohistochemical staining showed the cells were positive for MIC-2 (CD99).
Positive_regulation (positive) of MIC-2
2) Confidence 0.50 Published 2008 Journal Neurol. Med. Chir. (Tokyo) Section Abstract Doc Link 18296876 Disease Relevance 1.19 Pain Relevance 0.25
CT-guided fine-needle aspiration biopsy revealed a high-grade primitive small round cell tumor with the tumor cells being strongly positive for CD99 and vimentin.
Positive_regulation (positive) of CD99 associated with cancer
3) Confidence 0.46 Published 2007 Journal Diagn. Cytopathol. Section Abstract Doc Link 17497665 Disease Relevance 0.53 Pain Relevance 0.09
Immunohistochemical staining showed positive reaction for bcl-2, calponin, cytokeratins, CD99, S100, muscle-specific antigen, smooth muscle antigen and vimentin.
Positive_regulation (reaction) of CD99 in smooth muscle
4) Confidence 0.46 Published 2010 Journal APMIS Section Abstract Doc Link 20402678 Disease Relevance 0.86 Pain Relevance 0.21
and CD99, and are also variably positive for Bcl-2; usually cytokeratins and desmin are negative.9
Positive_regulation (positive) of CD99
5) Confidence 0.39 Published 2010 Journal Rare Tumors Section Body Doc Link PMC2994496 Disease Relevance 0.95 Pain Relevance 0.16
All neoplastic cells were stained positive for MIC2-protein (CD99).
Positive_regulation (positive) of CD99
6) Confidence 0.38 Published 2006 Journal World J. Gastroenterol. Section Abstract Doc Link 17009412 Disease Relevance 1.16 Pain Relevance 0.09
A limited panel of antibodies can lead to an erroneous diagnosis; B-lymphoblastic lymphoma may be negative for CD45 and CD20 but positive for CD99 and even for keratin, mimicking Ewing's sarcoma.
Positive_regulation (positive) of CD99 associated with sarcoma and precursor cell lymphoblastic leukemia-lymphoma
7) Confidence 0.13 Published 1998 Journal Am. J. Surg. Pathol. Section Abstract Doc Link 9669342 Disease Relevance 0.94 Pain Relevance 0
Immunohistochemical studies were positive for CD99, S-100, and CD45 and negative for desmin, actin, chromogranin, epithelial membrane antigen (EMA), and cytokeratin.
Positive_regulation (positive) of CD99
8) Confidence 0.11 Published 2007 Journal Quintessence Int Section Abstract Doc Link 17432791 Disease Relevance 1.02 Pain Relevance 0.16
All cell cultures were more than 90% positive for CD47, CD55 and CD99, between 65 and 95% for CD90 and CD46, between 30 and 92% for CD56 and CD63, between 5 and 60% for CD140b, between 0 and 20% for CD141.
Neg (negative) Positive_regulation (positive) of CD99
9) Confidence 0.09 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2850899 Disease Relevance 0.92 Pain Relevance 0.03
Immunihistochemically, the minor sex cord elements are positive for inhibin, calretinin, CD99, CD56, antikeratin antibody KL1 and MIC. [2,6]
Positive_regulation (positive) of CD99
10) Confidence 0.08 Published 2008 Journal Cases J Section Body Doc Link PMC2579288 Disease Relevance 1.14 Pain Relevance 0
Immunihistochemically, the minor sex cord elements are positive for inhibin, calretinin, CD99, CD56, antikeratin antibody KL1 and MIC [2,7].
Positive_regulation (positive) of CD99
11) Confidence 0.07 Published 2007 Journal Diagn Pathol Section Body Doc Link PMC2217290 Disease Relevance 1.18 Pain Relevance 0.06
Diffuse membranous MIC2 positivity was more in keeping with a Ewing's sarcoma/PNET than neuroendocrine carcinoma and a synovial sarcoma that also shows MIC2 and cytoplasmic expression.
Positive_regulation (shows) of MIC2 associated with sarcoma, neuroendocrine cancer, synovial sarcoma and primitive neuroectodermal tumors
12) Confidence 0.07 Published 2010 Journal J Med Case Reports Section Body Doc Link PMC2848680 Disease Relevance 2.30 Pain Relevance 0.07
Synovial sarcoma are also positive for EMA, vimentin, BCL-2, CD99 and calponin.
Positive_regulation (positive) of CD99 associated with synovial sarcoma
13) Confidence 0.06 Published 2006 Journal Cytojournal Section Body Doc Link PMC1562442 Disease Relevance 0.82 Pain Relevance 0
The neoplastic cells were positive for vimentin, alpha smooth muscle actin, osteonectin, CD99, and S100 in the chondroblastic portion, but negative for cytokeratin, epithelial membrane antigen, desmin, myogenin, CD34, and c-kit.
Positive_regulation (positive) of CD99 in smooth muscle
14) Confidence 0.03 Published 2007 Journal BMC Cancer Section Body Doc Link PMC1878495 Disease Relevance 0.57 Pain Relevance 0.04

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