INT76497

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Context Info
Confidence 0.21
First Reported 1998
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.08
Pain Relevance 1.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Adra2c) cytoplasm (Adra2c) signal transducer activity (Adra2c)
Anatomy Link Frequency
spinal cord 1
Adra2c (Rattus norvegicus)
Pain Link Frequency Relevance Heat
qutenza 3 99.74 Very High Very High Very High
Spinal cord 5 98.04 Very High Very High Very High
analgesia 1 93.40 High High
Clonidine 3 92.88 High High
Dorsal horn 1 80.24 Quite High
antagonist 1 78.72 Quite High
substance P 3 73.56 Quite High
primary afferent fibers 1 72.44 Quite High
agonist 2 66.80 Quite High
Enkephalin 1 54.72 Quite High
Disease Link Frequency Relevance Heat
Aids-related Complex 1 79.40 Quite High
Nociception 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Differential distribution of alpha2A and alpha2C adrenergic receptor immunoreactivity in the rat spinal cord.
Transcription (distribution) of alpha2C in spinal cord associated with qutenza and spinal cord
1) Confidence 0.21 Published 1998 Journal J. Neurosci. Section Title Doc Link 9671679 Disease Relevance 0 Pain Relevance 0.74
Though expression of mRNA of alpha2B-, as well as alpha2A- and alpha2C-adrenoceptor subtypes was demonstrated in gastric mucosa of the rat, the hydrophilic ST-91, given peripherally (orally, subcutaneously), failed to exert mucosal protection, in contrast with clonidine and rilmenidine which were also effective.
Transcription (expression) of alpha2C-adrenoceptor associated with clonidine
2) Confidence 0.21 Published 2007 Journal Neurochem. Int. Section Abstract Doc Link 17707950 Disease Relevance 0.08 Pain Relevance 0.33

General Comments

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