INT76527

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Context Info
Confidence 0.14
First Reported 1998
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 5
Total Number 5
Disease Relevance 1.73
Pain Relevance 3.40

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (EIF2C2) nucleus (EIF2C2) translation (EIF2C2)
cytoplasm (EIF2C2)
Anatomy Link Frequency
neurons 4
EIF2C2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Dynorphin 14 100.00 Very High Very High Very High
ketamine 10 99.16 Very High Very High Very High
Dorsal horn neuron 12 98.92 Very High Very High Very High
anesthesia 12 98.76 Very High Very High Very High
Dorsal horn 4 98.28 Very High Very High Very High
halothane 12 96.92 Very High Very High Very High
Spinal cord 14 91.96 High High
Endogenous opioid 2 79.84 Quite High
Neuronal excitability 2 66.96 Quite High
Enkephalin 2 25.00 Low Low
Disease Link Frequency Relevance Heat
Injury 14 95.16 Very High Very High Very High
Pressure And Volume Under Development 2 94.60 High High
Frailty 10 91.12 High High
Stress 11 5.00 Very Low Very Low Very Low
Cancer 10 5.00 Very Low Very Low Very Low
Disease 4 5.00 Very Low Very Low Very Low
Sprains And Strains 2 5.00 Very Low Very Low Very Low
Intellectual Impairment 1 5.00 Very Low Very Low Very Low
Immunotherapy Of Cancer 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
OPC, Q10:
Gene_expression (OPC) of Q10
1) Confidence 0.14 Published 2007 Journal Philos Ethics Humanit Med Section Body Doc Link PMC2186350 Disease Relevance 0 Pain Relevance 0
Two double-labeling experiments revealed that increased PPD mRNA and dynorphin peptide expression were found exclusively in dorsal horn neurons.
Gene_expression (expression) of PPD mRNA in neurons associated with dynorphin and dorsal horn neuron
2) Confidence 0.04 Published 1998 Journal J. Neurotrauma Section Abstract Doc Link 9674552 Disease Relevance 0.55 Pain Relevance 0.51
The number of neurons expressing PPD mRNA in each rat was significantly positively correlated with its motor dysfunction.
Gene_expression (expressing) of PPD mRNA in neurons
3) Confidence 0.04 Published 1998 Journal J. Neurotrauma Section Abstract Doc Link 9674552 Disease Relevance 0.65 Pain Relevance 0.70
The number of neurons expressing PPD mRNA dramatically increased in the superficial dorsal horn ipsilateral to the formalin injection in the control group compared to the contralateral side.
Gene_expression (expressing) of PPD mRNA in neurons associated with dorsal horn
4) Confidence 0.02 Published 1998 Journal Brain Res. Section Abstract Doc Link 9804904 Disease Relevance 0.30 Pain Relevance 1.09
However, the number of PPD mRNA-expressing neurons in both the ketamine and nitrous oxide groups was significantly less than the halothane group.
Gene_expression (expressing) of PPD mRNA in neurons associated with ketamine and halothane
5) Confidence 0.01 Published 1998 Journal Brain Res. Section Abstract Doc Link 9804904 Disease Relevance 0.22 Pain Relevance 1.11

General Comments

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