INT76609

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Context Info
Confidence 0.20
First Reported 1998
Last Reported 2006
Negated 1
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.97
Pain Relevance 0.79

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (NFKB1) mitochondrion (NFKB1) cytoplasm (NFKB1)
cytosol (NFKB1) signal transduction (NFKB1) nucleolus (NFKB1)
NFKB1 (Homo sapiens)
Pain Link Frequency Relevance Heat
nMDA receptor 7 99.76 Very High Very High Very High
ketamine 11 97.76 Very High Very High Very High
analgesia 1 88.96 High High
Inflammation 2 82.72 Quite High
withdrawal 1 82.44 Quite High
antagonist 1 57.64 Quite High
cINOD 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Heart Rate Under Development 1 97.12 Very High Very High Very High
Skin Cancer 7 93.72 High High
Adhesions 1 89.16 High High
Hallucination 1 87.08 High High
Injury 1 85.60 High High
INFLAMMATION 3 82.72 Quite High
Necrosis 1 74.64 Quite High
Cancer 1 74.28 Quite High
Schizophrenia 1 55.76 Quite High
Metastasis 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
NF-kappaB activation was measured using an assay that detects changes in the expression of a luciferase reporter gene under the direct control of NF-kappaB transcriptional activity.
Regulation (changes) of Regulation (control) of NF-kappaB
1) Confidence 0.20 Published 2006 Journal Melanoma Res. Section Abstract Doc Link 16432451 Disease Relevance 0.73 Pain Relevance 0.04
Although in humans NMDA receptors may not be involved in the regulation of PPI and P50 reduction, the most likely explanation for the lack of effect of ketamine on these sensory gating paradigms is the dose used in this experiment.
Neg (not) Regulation (involved) of Regulation (regulation) of P50 associated with ketamine and nmda receptor
2) Confidence 0.17 Published 1998 Journal Psychopharmacology (Berl.) Section Abstract Doc Link 9683005 Disease Relevance 0.24 Pain Relevance 0.75

General Comments

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