INT76623

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Context Info
Confidence 0.33
First Reported 1998
Last Reported 1998
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.63
Pain Relevance 0.62

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (Fen1) mitochondrion (Fen1) nucleolus (Fen1)
nucleus (Fen1) DNA binding (Fen1)
Fen1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
agonist 8 94.32 High High
Hippocampus 2 92.60 High High
Raphe 4 88.92 High High
fluoxetine 4 75.00 Quite High
Disease Link Frequency Relevance Heat
Appetite Loss 8 99.32 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, the ability of treatments which impair 5-HT neurotransmission to reverse FEN and FLU induced suppression of food intake may depend upon whether this impairment is acute and reversible (8-OH-DPAT), or chronic and irreversible (5,7-DHT).
Negative_regulation (reverse) of FEN
1) Confidence 0.33 Published 1998 Journal Brain Res. Section Abstract Doc Link 9685586 Disease Relevance 0.30 Pain Relevance 0.23
In 5,7-DHT treated rats, however, the ability of 8-OH-DPAT (125 microg/kg) to block FEN and FLU induced anorexia was attenuated.
Negative_regulation (block) of FEN associated with appetite loss
2) Confidence 0.33 Published 1998 Journal Brain Res. Section Abstract Doc Link 9685586 Disease Relevance 0.33 Pain Relevance 0.39

General Comments

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