INT76682

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Context Info
Confidence 0.17
First Reported 1998
Last Reported 1998
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 3.15
Pain Relevance 0.87

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Il1rap) intracellular (Il1rap) protein binding, bridging (Il1rap)
protein complex (Il1rap) signal transducer activity (Il1rap)
Anatomy Link Frequency
cortex 3
hypothalamus 1
Il1rap (Rattus norvegicus)
Pain Link Frequency Relevance Heat
antagonist 4 99.62 Very High Very High Very High
cytokine 14 96.56 Very High Very High Very High
Neuropeptide 8 85.40 High High
Opioid 2 83.92 Quite High
Disease Link Frequency Relevance Heat
Cancer 22 92.80 High High
Appetite Loss 14 92.44 High High
Necrosis 2 78.56 Quite High
Prostate Cancer 6 75.00 Quite High
Disease 2 62.80 Quite High
Neurologic Manifestations 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
IL-1 receptor antagonist (IL-1Ra) mRNA and IL-1 receptor type I mRNA levels were also significantly increased in the cortex and hypothalamus.
Positive_regulation (increased) of Transcription (levels) of IL-1 receptor type I mRNA in cortex associated with antagonist
1) Confidence 0.17 Published 1998 Journal Am. J. Physiol. Section Abstract Doc Link 9688694 Disease Relevance 1.58 Pain Relevance 0.43
IL-1 receptor antagonist (IL-1Ra) mRNA and IL-1 receptor type I mRNA levels were also significantly increased in the cortex and hypothalamus.
Positive_regulation (increased) of in hypothalamus Transcription (levels) of IL-1 receptor type I mRNA in cortex associated with antagonist
2) Confidence 0.06 Published 1998 Journal Am. J. Physiol. Section Abstract Doc Link 9688694 Disease Relevance 1.58 Pain Relevance 0.43

General Comments

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