INT76835

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.10
First Reported 1998
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.89
Pain Relevance 0.96

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Ednra) plasma membrane (Ednra) signal transducer activity (Ednra)
Anatomy Link Frequency
Nerve 2
paw 2
Ednra (Mus musculus)
Pain Link Frequency Relevance Heat
Hyperalgesia 6 99.58 Very High Very High Very High
agonist 2 99.48 Very High Very High Very High
qutenza 8 98.56 Very High Very High Very High
antagonist 5 92.12 High High
Action potential 11 45.68 Quite Low
depression 4 5.00 Very Low Very Low Very Low
Calcium channel 2 5.00 Very Low Very Low Very Low
tetrodotoxin 1 5.00 Very Low Very Low Very Low
withdrawal 1 5.00 Very Low Very Low Very Low
conotoxin 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hyperalgesia 9 99.58 Very High Very High Very High
Nociception 4 92.96 High High
Arrhythmias 2 Under Development 1 71.12 Quite High
Congenital Anomalies 8 5.00 Very Low Very Low Very Low
Increased Venous Pressure Under Development 5 5.00 Very Low Very Low Very Low
Depression 4 5.00 Very Low Very Low Very Low
Sprains And Strains 4 5.00 Very Low Very Low Very Low
Poisoning 3 5.00 Very Low Very Low Very Low
Dislocations 2 5.00 Very Low Very Low Very Low
Aging 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Hyperalgesia induced by 5-HT was abolished by simultaneous injection of endothelin-1 or the endothelin ET(B) receptor agonist IRL 1620 (each at 30 pmol/paw).
Negative_regulation (abolished) of Gene_expression (injection) of endothelin ET in paw associated with hyperalgesia and agonist
1) Confidence 0.10 Published 1998 Journal Eur. J. Pharmacol. Section Abstract Doc Link 9698200 Disease Relevance 0.82 Pain Relevance 0.96
Nerve-evoked contraction of the ETA was fully blocked within 1–2 days of BoNT/A injection.
Negative_regulation (blocked) of Gene_expression (contraction) of ETA in Nerve
2) Confidence 0.05 Published 2008 Journal The Journal of Physiology Section Body Doc Link PMC2538785 Disease Relevance 0.07 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox