INT76892

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.69
First Reported 1998
Last Reported 2010
Negated 3
Speculated 0
Reported most in Body
Documents 45
Total Number 49
Disease Relevance 23.60
Pain Relevance 7.56

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (FGFR1) extracellular region (FGFR1) cytoplasmic membrane-bounded vesicle (FGFR1)
plasma membrane (FGFR1) nucleus (FGFR1) cytoplasm (FGFR1)
Anatomy Link Frequency
fibroblast 9
endometrium 6
brain 2
keratinocyte 2
neuronal 2
FGFR1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 107 100.00 Very High Very High Very High
Hippocampus 97 100.00 Very High Very High Very High
adenocard 25 100.00 Very High Very High Very High
Dismenorea 21 100.00 Very High Very High Very High
Nerve growth factor 9 100.00 Very High Very High Very High
Snapping jaw 4 98.88 Very High Very High Very High
agonist 170 98.84 Very High Very High Very High
ischemia 161 98.76 Very High Very High Very High
Substantia nigra 18 98.76 Very High Very High Very High
Inflammation 219 97.40 Very High Very High Very High
Disease Link Frequency Relevance Heat
Injury 110 100.00 Very High Very High Very High
Epilepsy 44 100.00 Very High Very High Very High
Urological Neuroanatomy 22 100.00 Very High Very High Very High
Dysmenorrhea 21 100.00 Very High Very High Very High
Death 256 99.98 Very High Very High Very High
Post-traumatic Stress Disorder 124 99.60 Very High Very High Very High
Pancreatic Cancer 8 99.60 Very High Very High Very High
Synovial Chondromatosis 5 99.28 Very High Very High Very High
Cancer 308 99.16 Very High Very High Very High
Asthma 171 99.10 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This study was designed to evaluate if adenomyosis expresses bFGF and FGF-R, and if present, to compare bFGF and FGF-R expression in adenomyosis and autologous endometrium.
Gene_expression (expresses) of FGF-R in endometrium associated with dismenorea
1) Confidence 0.69 Published 2001 Journal Menopause Section Abstract Doc Link 11528364 Disease Relevance 0.46 Pain Relevance 0.27
This study was designed to evaluate if adenomyosis expresses bFGF and FGF-R, and if present, to compare bFGF and FGF-R expression in adenomyosis and autologous endometrium.
Gene_expression (expression) of FGF-R in endometrium associated with dismenorea
2) Confidence 0.69 Published 2001 Journal Menopause Section Abstract Doc Link 11528364 Disease Relevance 0.46 Pain Relevance 0.27
OBJECTIVES: Basic fibroblast growth factor (bFGF) is an angiogenic growth factor present in human endometrium and myometrium.
Gene_expression (present) of Basic fibroblast growth factor in endometrium
3) Confidence 0.69 Published 2001 Journal Menopause Section Abstract Doc Link 11528364 Disease Relevance 0.27 Pain Relevance 0.24
The expression and intensity of staining for bFGF, FGF-R, and PCNA were evaluated in the glandular epithelium and stroma of adenomyosis and endometrium.
Gene_expression (expression) of FGF-R in endometrium
4) Confidence 0.69 Published 2001 Journal Menopause Section Body Doc Link 11528364 Disease Relevance 0.17 Pain Relevance 0
Adenomyosis demonstrates increased expression of the basic fibroblast growth factor receptor/ligand system compared with autologous endometrium.
Gene_expression (expression) of basic fibroblast growth factor in endometrium associated with dismenorea
5) Confidence 0.69 Published 2001 Journal Menopause Section Title Doc Link 11528364 Disease Relevance 0.28 Pain Relevance 0.27
This study was designed to evaluate if adenomyosis expresses bFGF and FGF-R, and if present, to compare bFGF and FGF-R expression in adenomyosis and autologous endometrium.
Gene_expression (expression) of FGF-R in endometrium associated with dismenorea
6) Confidence 0.60 Published 2001 Journal Menopause Section Abstract Doc Link 11528364 Disease Relevance 0.46 Pain Relevance 0.27
Several FGFs, including FGF-1, -2, -3, -4, -5, -6, and -7, and several FGFR variants, among them the 2 immunoglobulin-like form and the IIIc splice variant of FGFR-1 and the keratinocyte growth factor receptor, a splice variant of FGFR-2, are expressed in human pancreatic cancer cell lines and are overexpressed in human pancreatic cancers or in the pancreas of chronic pancreatitis and, therefore, may play important roles in the pathobiology of these pancreatic diseases.
Gene_expression (expressed) of FGFR-1 in keratinocyte associated with pancreatitis, pancreatic cancer and chronic pancreatitis
7) Confidence 0.58 Published 1998 Journal Pancreas Section Abstract Doc Link 9700949 Disease Relevance 0.62 Pain Relevance 0.24
Several FGFs, including FGF-1, -2, -3, -4, -5, -6, and -7, and several FGFR variants, among them the 2 immunoglobulin-like form and the IIIc splice variant of FGFR-1 and the keratinocyte growth factor receptor, a splice variant of FGFR-2, are expressed in human pancreatic cancer cell lines and are overexpressed in human pancreatic cancers or in the pancreas of chronic pancreatitis and, therefore, may play important roles in the pathobiology of these pancreatic diseases.
Gene_expression (expressed) of FGF-1 in keratinocyte associated with pancreatitis, pancreatic cancer and chronic pancreatitis
8) Confidence 0.58 Published 1998 Journal Pancreas Section Abstract Doc Link 9700949 Disease Relevance 0.62 Pain Relevance 0.24
In biopsies from asthmatic patients, Hoshino et al [52], showed higher expression of basic fibroblast growth factor (bFGF) and angiogenin, with significant correlations between the vascular area and the number of angiogenic factor-positive cells within the airways.
Gene_expression (expression) of basic fibroblast growth factor in fibroblast associated with asthma
9) Confidence 0.47 Published 2010 Journal Respir Res Section Body Doc Link PMC2955663 Disease Relevance 0.41 Pain Relevance 0.17
Interestingly, a positive correlation between FGF-1 expression and pack-years was found, indicating that the degree of pulmonary FGF-1 expression may be related to the amount of airway exposure to smoke [68].
Gene_expression (expression) of FGF-1
10) Confidence 0.37 Published 2010 Journal Respir Res Section Body Doc Link PMC2955663 Disease Relevance 0.82 Pain Relevance 0
An increased expression of FGF-1 and FGF-2 was found by Kranenburg et al. [68] in the bronchial epithelium of COPD patients.
Gene_expression (expression) of FGF-1 in epithelium associated with pulmonary disease
11) Confidence 0.37 Published 2010 Journal Respir Res Section Body Doc Link PMC2955663 Disease Relevance 1.04 Pain Relevance 0
By so taking into account between-group heterogeneity, Welch-SAM identified a set of up regulated genes that were not detected by t-SAM.
Neg (not) Gene_expression (detected) of t-SAM
12) Confidence 0.31 Published 2002 Journal BMC Genomics Section Body Doc Link PMC137578 Disease Relevance 0.06 Pain Relevance 0
In the comparison of expression levels of more than 5000 probe sets between normal subjects and brachial plexus injury patients, we adopt both SAM and Westfall & Young algorithms using regular t statistics assuming equal variances and t statistics assuming unequal variances (hereafter called Welch statistics).
Gene_expression (expression) of SAM in brachial plexus associated with injury
13) Confidence 0.27 Published 2002 Journal BMC Genomics Section Body Doc Link PMC137578 Disease Relevance 0.46 Pain Relevance 0.07
The algorithm of SAM proposed by Tusher, et al.[3] provides an estimate of the FDR for each value of the parameter ?
Gene_expression (proposed) of SAM
14) Confidence 0.27 Published 2002 Journal BMC Genomics Section Body Doc Link PMC137578 Disease Relevance 0 Pain Relevance 0
OBJECTIVES: Basic fibroblast growth factor (bFGF) is an angiogenic growth factor present in human endometrium and myometrium.
Gene_expression (present) of Basic fibroblast growth factor in myometrium
15) Confidence 0.23 Published 2001 Journal Menopause Section Abstract Doc Link 11528364 Disease Relevance 0.27 Pain Relevance 0.24
The proposed model [8] states that the infiltrating monocytes/macrophages produce VEGF (vascular endothelial growth factor), bFGF (basic fibroblast growth factor) and other factors which act on both the endothelium and the smooth muscle cells thereby inducing more VEGF production from these cells.
Gene_expression (produce) of basic fibroblast growth factor in smooth muscle cells
16) Confidence 0.16 Published 2003 Journal J Transl Med Section Body Doc Link PMC239962 Disease Relevance 1.07 Pain Relevance 0.12
The expression of fibroblast growth factor-2 (FGF-2) and fibroblast growth factor receptor-1 (FGFR-1) in two cases of SC of the temporomandibular joint (TMJ) were immunohistochemically studied.
Gene_expression (expression) of FGFR-1 in TMJ associated with snapping jaw and synovial chondromatosis
17) Confidence 0.14 Published 2002 Journal Int J Oral Maxillofac Surg Section Abstract Doc Link 12418570 Disease Relevance 0.64 Pain Relevance 0.36
The best candidate human ortholog to T04A8.12 is FRAG1 (fibroblast growth factor receptor activating gene 1, Q9UHJ9).
Gene_expression (is) of fibroblast growth factor receptor in fibroblast
18) Confidence 0.12 Published 2004 Journal BMC Genomics Section Body Doc Link PMC533873 Disease Relevance 0.15 Pain Relevance 0
The expression of NGF (Trk-A) and bFGF (flg) receptors paralleled the switch in trophic requirement.
Gene_expression (expression) of bFGF associated with nerve growth factor
19) Confidence 0.12 Published 2001 Journal J. Neurosci. Section Abstract Doc Link 11698599 Disease Relevance 0.30 Pain Relevance 0.63
It has been shown that native, intact amniotic membrane (AM) epithelium contains higher levels of epidermal growth factor, keratinocyte growth factor, hepatocyte growth factor, and basic fibroblast growth factor compared with epithelially denuded AM.
Gene_expression (levels) of basic fibroblast growth factor in fibroblast
20) Confidence 0.11 Published 2008 Journal Clinical ophthalmology (Auckland, N.Z.) Section Body Doc Link PMC2693999 Disease Relevance 0 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox