INT76931

Context Info Confidence 0.45 First Reported 1998 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 2 Total Number 2 Disease Relevance 1.35 Pain Relevance 0.08

Golgi apparatus (MLANA) endoplasmic reticulum (MLANA)

Anatomy Link Frequency node 1 MLANA (Homo sapiens)

Pain Link Frequency Relevance Heat abdominal pain 1 82.44 anesthesia 1 5.00

Disease Link Frequency Relevance Heat Cancer 7 98.74 Nevus 1 88.88 Diarrhoea 1 82.96 Abdominal Pain 1 82.44 Melanoma 6 81.44 Metastasis 3 65.84 Disease 1 65.12 Skin Cancer 2 50.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Although no tumor cells contained apparent brown pigment, most were found to be positive for S-100 protein, HMB-45, Melan-A, and vimentin.

Positive_regulation (positive) of Melan-A associated with cancer

1) Confidence 0.45 Published 2010 Journal Turk J Gastroenterol Section Abstract Doc Link 20533113 Disease Relevance 1.29 Pain Relevance 0.08

Ten patients had positive sentinel node(s) by standard histopathologic examination, and all of these nodes were also positive for MART-1 and tyrosinase.

Positive_regulation (positive) of MART-1 in node

2) Confidence 0.15 Published 1998 Journal J. Am. Coll. Surg. Section Body Doc Link 9704966 Disease Relevance 0.07 Pain Relevance 0

General Comments

This test has worked.