INT76957

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Context Info
Confidence 0.57
First Reported 1998
Last Reported 2000
Negated 0
Speculated 0
Reported most in Title
Documents 6
Total Number 6
Disease Relevance 2.82
Pain Relevance 1.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (ITGB3) plasma membrane (ITGB3)
Anatomy Link Frequency
platelet 6
ITGB3 (Homo sapiens)
Pain Link Frequency Relevance Heat
cva 5 100.00 Very High Very High Very High
Angina 11 99.08 Very High Very High Very High
aspirin 5 91.44 High High
antagonist 1 85.68 High High
Disease Link Frequency Relevance Heat
Acute Coronary Syndrome 11 99.50 Very High Very High Very High
Cv General 3 Under Development 11 99.08 Very High Very High Very High
Myocardial Infarction 10 97.44 Very High Very High Very High
Syndrome 3 96.16 Very High Very High Very High
Stroke 3 94.48 High High
Death 2 93.60 High High
Thrombosis 4 85.60 High High
Increased Venous Pressure Under Development 1 84.88 Quite High
Cv General 4 Under Development 1 25.00 Low Low
Cardiovascular Disease 1 25.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Inhibition of platelet glycoprotein IIb/IIIa with eptifibatide in patients with acute coronary syndromes.
Negative_regulation (Inhibition) of platelet glycoprotein IIb/IIIa in platelet associated with acute coronary syndrome and cva
1) Confidence 0.57 Published 1998 Journal N. Engl. J. Med. Section Title Doc Link 9705684 Disease Relevance 0.28 Pain Relevance 0.23
Cost-effectiveness of platelet glycoprotein IIb/IIIa inhibition with eptifibatide in patients with non-ST-elevation acute coronary syndromes.
Negative_regulation (inhibition) of platelet glycoprotein IIb/IIIa in platelet associated with acute coronary syndrome
2) Confidence 0.42 Published 2000 Journal Circulation Section Title Doc Link 10653826 Disease Relevance 0.19 Pain Relevance 0.09
Eptifibatide, a synthetic cyclic heptapeptide, is a selective high-affinity inhibitor of the platelet glycoprotein IIb/IIIa receptor, which is involved in platelet aggregation.
Negative_regulation (inhibitor) of platelet glycoprotein IIb/IIIa in platelet
3) Confidence 0.42 Published 1998 Journal N. Engl. J. Med. Section Abstract Doc Link 9705684 Disease Relevance 0.25 Pain Relevance 0.12
Management of patients with acute coronary syndromes in the United States by platelet glycoprotein IIb/IIIa inhibition.
Negative_regulation (inhibition) of platelet glycoprotein IIb/IIIa in platelet associated with acute coronary syndrome and cva
4) Confidence 0.31 Published 2000 Journal Circulation Section Title Doc Link 10973836 Disease Relevance 0.54 Pain Relevance 0.28
Incorporating platelet glycoprotein IIb/IIIa inhibition in critical pathways: unstable angina/non-ST-segment elevation myocardial infarction.
Negative_regulation (inhibition) of platelet glycoprotein IIb/IIIa in platelet associated with angina and myocardial infarction
5) Confidence 0.07 Published 1999 Journal Clin Cardiol Section Title Doc Link 10492851 Disease Relevance 0.69 Pain Relevance 0.26
Platelet glycoprotein IIb/IIIa receptor (GPIIb/IIIa) blockade represents a significant advance in interventional cardiology and treatment of acute ischaemic syndromes.
Negative_regulation (blockade) of Platelet glycoprotein IIb/IIIa in Platelet associated with syndrome
6) Confidence 0.02 Published 2000 Journal Expert Opin Investig Drugs Section Abstract Doc Link 11060829 Disease Relevance 0.87 Pain Relevance 0.15

General Comments

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