INT77031

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Context Info
Confidence 0.51
First Reported 1998
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 4.32
Pain Relevance 0.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (LIPG) extracellular space (LIPG) extracellular region (LIPG)
lipid metabolic process (LIPG)
Anatomy Link Frequency
T-cell 1
LIPG (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 43 100.00 Very High Very High Very High
Inflammatory response 3 97.80 Very High Very High Very High
Inflammation 30 89.28 High High
Angina 7 48.64 Quite Low
chemokine 9 47.72 Quite Low
Neuropeptide 13 5.00 Very Low Very Low Very Low
Osteoarthritis 11 5.00 Very Low Very Low Very Low
behavioral therapy 8 5.00 Very Low Very Low Very Low
Serotonin 6 5.00 Very Low Very Low Very Low
Cholecystokinin 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Benign Prostatic Hypertrophy 115 100.00 Very High Very High Very High
Prostate Cancer 45 100.00 Very High Very High Very High
Natriuresis 1 100.00 Very High Very High Very High
Disorder Of Lipid Metabolism 9 99.84 Very High Very High Very High
Viral Infection 2 98.40 Very High Very High Very High
INFLAMMATION 38 97.40 Very High Very High Very High
Hypersensitivity 1 96.68 Very High Very High Very High
Disease 34 88.84 High High
Obesity 274 86.52 High High
Apoptosis 10 80.08 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Those expressed extracellularly and with an average expression level at least three-fold greater in BPH RNA pools than in the prostate cancer RNA pools included: CDH13, CHRNB1, COL4A5, EFEMP2, EMP3, F10 (16-fold), FGF2, FGFBP1 (10-fold), IGF1, IGF2 (18-fold), LIPG, RARB, SGCA, SGCD, TGFB1, TGFB3 (14-fold), TGFBR2 and TIMP2 of the “high in BPH, moderate in prostate cancer” group; SMOC1 (26-fold) in the “high in BPH, low in prostate cancer” group; and SCGB3A1 (15-fold) and SCGB1A1 (14-fold) in the “moderate in BPH, low in prostate cancer” group.


Gene_expression (expressed) of LIPG associated with benign prostatic hypertrophy and prostate cancer
1) Confidence 0.51 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2793011 Disease Relevance 2.48 Pain Relevance 0
Levels of peroxisome proliferator-activated receptor gamma co-activator 1alpha mRNA were increased, while the expression of the genes encoding leptin, osteonectin, phosphodiesterase 3B, hormone-sensitive lipase, receptor A for natriuretic peptide, fatty acid translocase, lipoprotein lipase, uncoupling protein 2 and peroxisome proliferator-activated receptor gamma was decreased [39].
Gene_expression (expression) of lipoprotein lipase associated with natriuresis
2) Confidence 0.05 Published 2005 Journal J Int Soc Sports Nutr Section Body Doc Link PMC2129146 Disease Relevance 0.58 Pain Relevance 0
The action of lipoprotein lipase on chylomicrons and very low density lipoproteins produces remnant lipoproteins (RLP) rich in triglycerides (TG), cholesterol (C) and apolipoprotein E (apo E).
Gene_expression (action) of lipoprotein lipase associated with disorder of lipid metabolism
3) Confidence 0.01 Published 1998 Journal Atherosclerosis Section Abstract Doc Link 9712343 Disease Relevance 0.38 Pain Relevance 0
IL-26 is a T-cell-derived cytokine, normally expressed at low levels but over-expressed after viral infection [13].
Gene_expression (expressed) of cell-derived in T-cell associated with viral infection and cytokine
4) Confidence 0.01 Published 2003 Journal Cardiovasc Diabetol Section Body Doc Link PMC212422 Disease Relevance 0.88 Pain Relevance 0.26

General Comments

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