INT77054

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Context Info
Confidence 0.05
First Reported 1998
Last Reported 2006
Negated 1
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.70
Pain Relevance 0.96

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Timp2) aging (Timp2) extracellular region (Timp2)
nucleus (Timp2)
Timp2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cytokine 5 99.82 Very High Very High Very High
metalloproteinase 11 95.20 Very High Very High Very High
Snapping jaw 7 87.60 High High
pulpitis 1 73.68 Quite High
Disease Link Frequency Relevance Heat
Temporomandibular Joint Syndrome 7 87.60 High High
Cancer 1 75.00 Quite High
Necrosis 1 75.00 Quite High
Pulpitis 1 73.68 Quite High
Joint Instability 1 69.76 Quite High
Disease 5 63.08 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Relaxin produced a dose-dependent induction of collagenase-1 (MMP-1) and stromelysin-1 (MMP-3), but minimal modulation of TIMP-1 and TIMP-2 expression in the fibrocartilaginous cells.
Regulation (modulation) of Gene_expression (expression) of TIMP-2
1) Confidence 0.05 Published 1998 Journal Lab. Invest. Section Abstract Doc Link 9714180 Disease Relevance 0.47 Pain Relevance 0.52
These cytokines did not affect the expression of TIMP-1 or TIMP-2.
Neg (not) Regulation (affect) of Gene_expression (expression) of TIMP-2 associated with cytokine
2) Confidence 0.04 Published 2006 Journal J Endod Section Abstract Doc Link 16934628 Disease Relevance 0.22 Pain Relevance 0.45

General Comments

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