INT77213

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Context Info
Confidence 0.69
First Reported 1998
Last Reported 1998
Negated 0
Speculated 1
Reported most in Abstract
Documents 1
Total Number 6
Disease Relevance 0
Pain Relevance 2.55

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (ADORA2A) enzyme binding (ADORA2A) cell-cell signaling (ADORA2A)
signal transducer activity (ADORA2A)
Anatomy Link Frequency
striatum 3
nucleus accumbens 1
putamen 1
nucleus 1
ADORA2A (Homo sapiens)
Pain Link Frequency Relevance Heat
adenocard 66 100.00 Very High Very High Very High
Enkephalin 6 99.82 Very High Very High Very High
Nucleus accumbens 12 97.40 Very High Very High Very High
Dopamine 18 97.28 Very High Very High Very High
substance P 6 91.40 High High
Disease Link Frequency Relevance Heat
Disease 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Cellular distribution of adenosine A2A receptor mRNA in the primate striatum.
Transcription (distribution) of adenosine A2A receptor in striatum associated with adenocard and enkephalin
1) Confidence 0.69 Published 1998 Journal J. Comp. Neurol. Section Title Doc Link 9721905 Disease Relevance 0 Pain Relevance 0.60
By contrast, high expression of preproenkephalin A mRNA but no expression of adenosine A2A receptor mRNA was found in the nucleus basalis of Meynert.
Transcription (expression) of adenosine A2A receptor in nucleus associated with adenocard
2) Confidence 0.51 Published 1998 Journal J. Comp. Neurol. Section Abstract Doc Link 9721905 Disease Relevance 0 Pain Relevance 0.43
Analysis on adjacent sections demonstrated a homogeneous overlapping expression of adenosine A2A receptor and preproenkephalin A mRNAs throughout nucleus caudatus, putamen, and nucleus accumbens.
Transcription (expression) of adenosine A2A receptor in putamen associated with nucleus accumbens and adenocard
3) Confidence 0.51 Published 1998 Journal J. Comp. Neurol. Section Abstract Doc Link 9721905 Disease Relevance 0 Pain Relevance 0.32
The cellular expression of adenosine A2A receptor mRNA in the adult monkey and human striatum was examined by using single and double in situ hybridization with ribonucleotide probes.
Spec (examined) Transcription (expression) of adenosine A2A receptor in striatum associated with adenocard
4) Confidence 0.51 Published 1998 Journal J. Comp. Neurol. Section Abstract Doc Link 9721905 Disease Relevance 0 Pain Relevance 0.23
These results demonstrate that there is a high expression of adenosine A2A receptor mRNA in the primate striatum that is extensively co-localized with dopamine D2 receptor and preproenkephalin A mRNAs.
Transcription (expression) of adenosine A2A receptor in striatum associated with dopamine and adenocard
5) Confidence 0.51 Published 1998 Journal J. Comp. Neurol. Section Abstract Doc Link 9721905 Disease Relevance 0 Pain Relevance 0.65
Analysis on adjacent sections demonstrated a homogeneous overlapping expression of adenosine A2A receptor and preproenkephalin A mRNAs throughout nucleus caudatus, putamen, and nucleus accumbens.
Transcription (expression) of adenosine A2A receptor in nucleus accumbens associated with nucleus accumbens and adenocard
6) Confidence 0.17 Published 1998 Journal J. Comp. Neurol. Section Abstract Doc Link 9721905 Disease Relevance 0 Pain Relevance 0.32

General Comments

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