INT77216

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Context Info
Confidence 0.75
First Reported 1998
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0
Pain Relevance 1.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

pigmentation (DRD2) plasma membrane (DRD2) signal transducer activity (DRD2)
Anatomy Link Frequency
striatum 1
basal ganglia 1
DRD2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Dopamine 103 100.00 Very High Very High Very High
Catechol-O-methyltransferase 34 99.80 Very High Very High Very High
adenocard 11 98.74 Very High Very High Very High
positron emission tomography 5 96.96 Very High Very High Very High
Nucleus accumbens 10 91.20 High High
substance P 1 87.96 High High
Limbic system 5 40.92 Quite Low
Enkephalin 6 25.00 Low Low
Neurotransmitter 30 5.00 Very Low Very Low Very Low
Serotonin 21 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Attention Deficit Hyperactivity Disorder 304 50.00 Quite Low
Tourette's Syndrome 17 21.60 Low Low
Syndrome 29 5.00 Very Low Very Low Very Low
Conduct Disorder 23 5.00 Very Low Very Low Very Low
Substance Abuse 18 5.00 Very Low Very Low Very Low
Depression 16 5.00 Very Low Very Low Very Low
Attention Deficit And Disruptive Behavior Disorders 13 5.00 Very Low Very Low Very Low
Tics 11 5.00 Very Low Very Low Very Low
Alcohol Addiction 10 5.00 Very Low Very Low Very Low
Anxiety Disorder 9 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
No significant association of gender with genotype or allele frequency of DRD2 and COMT was observed in either sample.
Localization (frequency) of DRD2 associated with catechol-o-methyltransferase
1) Confidence 0.75 Published 2007 Journal Behav Brain Funct Section Body Doc Link PMC1779796 Disease Relevance 0 Pain Relevance 0.26
These results demonstrate that there is a high expression of adenosine A2A receptor mRNA in the primate striatum that is extensively co-localized with dopamine D2 receptor and preproenkephalin A mRNAs.
Localization (co-localized) of dopamine D2 receptor in striatum associated with dopamine and adenocard
2) Confidence 0.55 Published 1998 Journal J. Comp. Neurol. Section Abstract Doc Link 9721905 Disease Relevance 0 Pain Relevance 0.63
Noble and Blum and associates had previously shown that Taq I D2A1 carriers had a significantly decreased dopamine D2 receptor in the basal ganglia.
Localization (decreased) of dopamine D2 receptor in basal ganglia associated with dopamine
3) Confidence 0.18 Published 2008 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2626918 Disease Relevance 0 Pain Relevance 0.29

General Comments

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