INT77322

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Context Info
Confidence 0.33
First Reported 1998
Last Reported 1998
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.86
Pain Relevance 1.51

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Npy1r) plasma membrane (Npy1r) molecular_function (Npy1r)
signal transducer activity (Npy1r)
Anatomy Link Frequency
nucleus accumbens 2
dentate gyrus 2
Npy1r (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Anterior cingulate cortex 2 99.92 Very High Very High Very High
fluoxetine 10 99.84 Very High Very High Very High
Nucleus accumbens 4 99.12 Very High Very High Very High
Anterior cingulate 2 98.12 Very High Very High Very High
antidepressant 4 87.28 High High
depression 8 85.04 High High
Serotonin 2 80.64 Quite High
Neuropeptide 4 78.32 Quite High
Disease Link Frequency Relevance Heat
Sprains And Strains 8 95.12 Very High Very High Very High
Depressive Disorder 2 86.56 High High
Depression 8 85.04 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In contrast, Y1 mRNA levels tended to be decreased by fluoxetine in the nucleus accumbens of the FSL rats, but increased in the FRL.
Negative_regulation (decreased) of Transcription (levels) of Y1 in nucleus accumbens associated with nucleus accumbens and fluoxetine
1) Confidence 0.33 Published 1998 Journal Brain Res. Mol. Brain Res. Section Abstract Doc Link 9729278 Disease Relevance 0.48 Pain Relevance 0.83
Y1 receptor mRNA expression was decreased in different cortical regions (retrosplenial, anterior cingulate, and occipital) and in the hippocampal dentate gyrus.
Negative_regulation (decreased) of Transcription (expression) of Y1 in dentate gyrus associated with anterior cingulate
2) Confidence 0.33 Published 1998 Journal Brain Res. Mol. Brain Res. Section Abstract Doc Link 9729278 Disease Relevance 0.38 Pain Relevance 0.67

General Comments

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