INT77377

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Context Info
Confidence 0.02
First Reported 1998
Last Reported 1998
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.48

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Fbln5) signal transduction (Cnr1) extracellular region (Fbln5)
aging (Cnr1) cell adhesion (Fbln5) plasma membrane (Cnr1)
Anatomy Link Frequency
tail 1
Cnr1 (Mus musculus)
Fbln5 (Mus musculus)
Pain Link Frequency Relevance Heat
Cannabinoid 10 100.00 Very High Very High Very High
intrathecal 1 97.28 Very High Very High Very High
antagonist 3 93.40 High High
tail-flick 1 92.52 High High
Antinociceptive 2 75.00 Quite High
agonist 1 48.40 Quite Low
Analgesic 1 25.00 Low Low
antinociception 1 25.00 Low Low

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We evaluated delta-9 tetrahydrocannabinol (Delta9-THC), delta-8 tetrahydrocannabinol (Delta8-THC), CP55,940 (CP55), 1-deoxy-11-hydroxy-Delta8-THC-dimethylheptyl (deoxy-HU210, a CB2-selective cannabinoid that also binds the CB1 receptor) and the endogenous cannabinoid anandamide (ANA) via i.c.v. and/or intrathecal (i.t.) routes of administration, alone and in combination with SR141716A (SR), a CB1 antagonist, using the tail-flick test.
CB1 receptor Binding (binds) of CP55 in tail associated with antagonist, cannabinoid, tail-flick and intrathecal
1) Confidence 0.02 Published 1998 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 9732392 Disease Relevance 0 Pain Relevance 0.48

General Comments

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