INT77383

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Context Info
Confidence 0.65
First Reported 1998
Last Reported 2010
Negated 0
Speculated 1
Reported most in Abstract
Documents 8
Total Number 9
Disease Relevance 4.14
Pain Relevance 1.55

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Tnni3)
Anatomy Link Frequency
heart 2
chest 1
Tnni3 (Mus musculus)
Pain Link Frequency Relevance Heat
anesthesia 28 99.92 Very High Very High Very High
Serotonin 16 99.48 Very High Very High Very High
Angina 15 97.80 Very High Very High Very High
ischemia 6 94.40 High High
Pain 3 68.88 Quite High
isoflurane 1 67.68 Quite High
imagery 3 5.00 Very Low Very Low Very Low
depression 2 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypertrophic Cardiomyopathy 42 100.00 Very High Very High Very High
Emergencies 2 98.96 Very High Very High Very High
Acute Coronary Syndrome 4 98.28 Very High Very High Very High
Infarction 1 97.98 Very High Very High Very High
Angina 8 97.80 Very High Very High Very High
Injury 24 97.60 Very High Very High Very High
Coronary Artery Disease 4 97.20 Very High Very High Very High
Myocardial Infarction 27 96.84 Very High Very High Very High
Heart Disease 5 95.88 Very High Very High Very High
Cv Unclassified Under Development 6 94.40 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The markers normally used include creatine kinase (CK), heart-fatty acid binding protein, myoglobin, TnI and ?
Gene_expression (include) of TnI in heart
1) Confidence 0.65 Published 2008 Journal British Journal of Sports Medicine Section Body Doc Link PMC2564766 Disease Relevance 0.26 Pain Relevance 0.07
We identified an HCM-causative mutation in one of the five most commonly mutated sarcomeric genes (MYH7, MYBPC3, TPM1, TNNI3, or TNNT2) in 40 cases, but we cannot exclude that other patients harbour mutations in any of the other genes that have been linked to HCM.
Gene_expression (identified) of TNNI3 associated with hypertrophic cardiomyopathy
2) Confidence 0.57 Published 2010 Journal J Transl Med Section Body Doc Link PMC2907326 Disease Relevance 0.44 Pain Relevance 0.05
Within the past few years, a number of new phrases, micro-infarction, minor cardiac damage and non-ischemic cardiac damage have been frequently used and discussed since cardiac troponin I (cTnI) was introduced.
Gene_expression (introduced) of cardiac troponin I associated with infarction
3) Confidence 0.20 Published 2001 Journal Clin. Lab. Section Abstract Doc Link 11596911 Disease Relevance 0.51 Pain Relevance 0.06
Cardiac troponin I (cTnI) concentration was measured preoperatively and over 72 h postoperatively, and the area under the curve (AUC) was calculated.
Gene_expression (concentration) of Cardiac troponin I
4) Confidence 0.17 Published 2010 Journal Basic Res. Cardiol. Section Abstract Doc Link 20495811 Disease Relevance 0.54 Pain Relevance 0.18
The aim of this study was to determine the prevalence and clinical significance of an elevated cardiac troponin I (cTnI) in patients presenting to the Emergency Department without chest pain.
Spec (determine) Gene_expression (prevalence) of cardiac troponin I in chest associated with angina and emergencies
5) Confidence 0.14 Published 2006 Journal Eur. J. Intern. Med. Section Abstract Doc Link 16490684 Disease Relevance 0.54 Pain Relevance 0.36
The detection of cardiac troponin I(cTnI), including serum or plasma, was evaluated in 114 patients with ischemic heart diseases or other heart diseases.
Gene_expression (detection) of cardiac troponin I in heart associated with coronary artery disease and heart disease
6) Confidence 0.11 Published 1998 Journal Hunan Yi Ke Da Xue Xue Bao Section Abstract Doc Link 10806770 Disease Relevance 0.40 Pain Relevance 0
Detection of cardiac troponin I (cTnI) in patients suspected of having an acute coronary syndrome is highly predictive for an adverse outcome.
Gene_expression (Detection) of cardiac troponin I associated with acute coronary syndrome
7) Confidence 0.10 Published 1998 Journal Clin. Chem. Section Abstract Doc Link 9732978 Disease Relevance 0.37 Pain Relevance 0.07
Analytical performance and clinical application of a new rapid bedside assay for the detection of serum cardiac troponin I.
Gene_expression (detection) of cardiac troponin I
8) Confidence 0.09 Published 1998 Journal Clin. Chem. Section Title Doc Link 9732978 Disease Relevance 0.61 Pain Relevance 0.15
The present study was designed to determine whether the measurement of serum levels of cardiac troponin I (cTnI), a highly sensitive and specific marker for cardiac injury, would help establish the diagnosis of myocardial infarction in two different types of anesthesia.


Gene_expression (levels) of cardiac troponin I associated with anesthesia, injury and myocardial infarction
9) Confidence 0.07 Published 2007 Journal Vascular Health and Risk Management Section Abstract Doc Link PMC2291320 Disease Relevance 0.47 Pain Relevance 0.60

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