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Context Info
Confidence 0.79
First Reported 1998
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 1.79
Pain Relevance 0.36

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (ZGLP1)
Anatomy Link Frequency
ileum 2
saliva 1
gut 1
ZGLP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Endocannabinoid 10 80.36 Quite High
agonist 10 76.96 Quite High
antagonist 2 68.20 Quite High
Neurotransmitter 4 54.40 Quite High
Inflammation 320 50.00 Quite Low
Paracetamol 3 45.68 Quite Low
Dopamine 4 39.20 Quite Low
nud 3 32.88 Quite Low
dopamine receptor 2 29.44 Quite Low
addiction 2 21.44 Low Low
Disease Link Frequency Relevance Heat
Monsters 1 96.88 Very High Very High Very High
Disease 11 95.96 Very High Very High Very High
Obesity 233 89.60 High High
Weight Gain 5 88.00 High High
Appetite Loss 16 84.88 Quite High
Diabetes Mellitus 111 80.48 Quite High
Overnutrition 15 78.80 Quite High
INFLAMMATION 360 50.00 Quite Low
Insulin Resistance 24 46.88 Quite Low
Dyspepsia 3 32.88 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The gut peptide glucagon-like peptide 1(7-36) amide (GLP-1) is released into the circulation after food intake.
Localization (released) of GLP-1 in gut
1) Confidence 0.79 Published 1998 Journal Am. J. Clin. Nutr. Section Abstract Doc Link 9734726 Disease Relevance 0.22 Pain Relevance 0
Exendin-4 (EX-4), an incretin-mimetic peptide hormone (containing 39 aminoacid residues) having GLP-1 like action[34], is secreted in the saliva (oral secretions)[3–6] and concentrated in the tail[3] of Gila monster lizard (Heloderma suspectum).
Localization (secreted) of GLP-1 in saliva associated with monsters
2) Confidence 0.20 Published 2010 Journal Indian Journal of Pharmaceutical Sciences Section Body Doc Link PMC2883206 Disease Relevance 0.85 Pain Relevance 0.06
Unlike other gastric bypass methods, this surgery also increases the release of gut hormones such as PYY and GLP-1 from the L-cells in the ileum, to give a profound degree of satiety [91].
Localization (release) of GLP-1 in ileum
3) Confidence 0.06 Published 2011 Journal Journal of Obesity Section Body Doc Link PMC2952901 Disease Relevance 0.61 Pain Relevance 0.17
As mentioned earlier, much of the success of gastric bypass surgery is related to the increase in satiety hormones (PYY and GLP-1) released from the ileum.
Localization (released) of GLP-1 in ileum
4) Confidence 0.05 Published 2011 Journal Journal of Obesity Section Body Doc Link PMC2952901 Disease Relevance 0.12 Pain Relevance 0.13

General Comments

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