INT77430

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Context Info
Confidence 0.57
First Reported 1998
Last Reported 1998
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.87
Pain Relevance 0.40

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

HTs (Homo sapiens)
Pain Link Frequency Relevance Heat
pruritus 4 97.36 Very High Very High Very High
Pain 1 96.84 Very High Very High Very High
Serotonin 1 92.36 High High
palliative 1 85.84 High High
Disease Link Frequency Relevance Heat
Pruritus 4 97.36 Very High Very High Very High
Vomiting 2 96.92 Very High Very High Very High
Pain 1 96.84 Very High Very High Very High
Cancer 2 82.80 Quite High
Malignant Neoplastic Disease 1 80.32 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We suggest that paroxetine's antipruritic effect may be explained by rapid downregulation of the 5-HTs receptors, which may have an important role in the generation of pruritus and pain.
Negative_regulation (downregulation) of HTs associated with pain and pruritus
1) Confidence 0.57 Published 1998 Journal J Pain Symptom Manage Section Abstract Doc Link 9737103 Disease Relevance 0.87 Pain Relevance 0.40

General Comments

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