INT775

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Context Info
Confidence 0.18
First Reported 1977
Last Reported 1982
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 3
Disease Relevance 0
Pain Relevance 1.02

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Nts) plasma membrane (Gnrhr) signal transducer activity (Gnrhr)
Anatomy Link Frequency
plasma 1
pituitary 1
Nts (Rattus norvegicus)
Gnrhr (Rattus norvegicus)
Pain Link Frequency Relevance Heat
substance P 6 100.00 Very High Very High Very High
Morphine 2 100.00 Very High Very High Very High
dopamine receptor 2 97.96 Very High Very High Very High
Catecholamine 2 96.04 Very High Very High Very High
fluoxetine 2 91.32 High High
Dopamine 2 91.12 High High
narcan 2 87.68 High High
opiate 2 86.64 High High
antagonist 1 78.80 Quite High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Neurotensin can inhibit LH and stimulate growth hormone presumably by a hypothalamic action since there was no effect on the release of these pituitary hormones by glands incubated in vitro.
Neurotensin Positive_regulation (stimulate) of growth hormone in pituitary
1) Confidence 0.18 Published 1982 Journal Ann. N. Y. Acad. Sci. Section Abstract Doc Link 6820240 Disease Relevance 0 Pain Relevance 0.16
In ovariectomized females, neurotensin was also capable of suppressing LH and elevating growth hormone following its intraventricular injection.
neurotensin Positive_regulation (elevating) of growth hormone
2) Confidence 0.12 Published 1982 Journal Ann. N. Y. Acad. Sci. Section Abstract Doc Link 6820240 Disease Relevance 0 Pain Relevance 0.21
Neurotensin (NT), substance P (SP) and morphine sulfate (MS) elevate plasma prolactin and growth hormone levels in both normal or estrogen-progesterone pretreated male rats.
Neurotensin Positive_regulation (elevate) of growth hormone in plasma associated with morphine and substance p
3) Confidence 0.11 Published 1977 Journal Endocrinology Section Abstract Doc Link 95701 Disease Relevance 0 Pain Relevance 0.64

General Comments

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