INT77595

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Context Info
Confidence 0.14
First Reported 1998
Last Reported 1998
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (ITGA1, VCAM1) plasma membrane (ITGA1, VCAM1) extracellular space (VCAM1)
aging (VCAM1)
Anatomy Link Frequency
PBL 2
ITGA1 (Homo sapiens)
VCAM1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adhesions 3 50.00 Quite Low
INFLAMMATION 2 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CONCLUSION: Some NSAIDs are able to inhibit the adhesion of PBL to HUVEC under conditions that resemble blood flow by interfering with the conformational change in VLA-4 that increases its affinity for VCAM-1.


VLA-4 Positive_regulation (increases) of VCAM-1 Binding (affinity) of in PBL
1) Confidence 0.14 Published 1998 Journal Arthritis Rheum. Section Body Doc Link 9751102 Disease Relevance 0 Pain Relevance 0

General Comments

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