INT77859

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.64
First Reported 1998
Last Reported 2002
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.34
Pain Relevance 0.94

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

pigmentation (MC1R) extracellular space (EDN1) extracellular region (EDN1)
plasma membrane (MC1R) signal transducer activity (MC1R) cell-cell signaling (EDN1)
Anatomy Link Frequency
NHM 1
EDN1 (Homo sapiens)
MC1R (Homo sapiens)
Pain Link Frequency Relevance Heat
melanocortin 1 receptor 13 100.00 Very High Very High Very High
Kinase C 1 86.80 High High
cytokine 2 56.16 Quite High
Disease Link Frequency Relevance Heat
Necrosis 2 95.64 Very High Very High Very High
Cancer 2 95.28 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
MSH receptor (MSH-R) binding activity was upregulated by UVB, IL-1alpha, -1beta and ET-1, but was downregulated by TNF-alpha.
ET-1 Positive_regulation (upregulated) of MSH-R
1) Confidence 0.64 Published 1998 Journal Br. J. Dermatol. Section Abstract Doc Link 9767234 Disease Relevance 0.34 Pain Relevance 0.12
Endothelin-1 increased MC1R mRNA level in NHM regardless of their melanin content.
Endothelin-1 Positive_regulation (increased) of MC1R mRNA in NHM associated with melanocortin 1 receptor
2) Confidence 0.20 Published 2002 Journal Pigment Cell Res. Section Abstract Doc Link 12453185 Disease Relevance 0 Pain Relevance 0.82

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox