INT77946

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Context Info
Confidence 0.24
First Reported 1996
Last Reported 1996
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 4
Disease Relevance 0
Pain Relevance 0.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (IL12A) extracellular region (IL12A) cytoplasm (IL12A)
Anatomy Link Frequency
NK cell 2
IL12A (Homo sapiens)
Pain Link Frequency Relevance Heat
Enkephalin 8 99.40 Very High Very High Very High
Neuropeptide 4 96.72 Very High Very High Very High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
RESULT: Met-enk promoted NK activity at 1 x 10(-8) - 1 x 10(-5) mol.L-1, increased TNF-alpha production both in vitro and in vivo, and enhanced IL-12 p35 gene transcription after ip 0.1 mg.kg-1 for 6 d.
Positive_regulation (increased) of Transcription (transcription) of IL-12
1) Confidence 0.24 Published 1996 Journal Zhongguo Yao Li Xue Bao Section Body Doc Link 9772675 Disease Relevance 0 Pain Relevance 0
RESULT: Met-enk promoted NK activity at 1 x 10(-8) - 1 x 10(-5) mol.L-1, increased TNF-alpha production both in vitro and in vivo, and enhanced IL-12 p35 gene transcription after ip 0.1 mg.kg-1 for 6 d.
Positive_regulation (enhanced) of Transcription (transcription) of IL-12
2) Confidence 0.16 Published 1996 Journal Zhongguo Yao Li Xue Bao Section Body Doc Link 9772675 Disease Relevance 0 Pain Relevance 0
RESULT: Met-enk promoted NK activity at 1 x 10(-8) - 1 x 10(-5) mol.L-1, increased TNF-alpha production both in vitro and in vivo, and enhanced IL-12 p35 gene transcription after ip 0.1 mg.kg-1 for 6 d.
Positive_regulation (after) of Transcription (transcription) of IL-12
3) Confidence 0.16 Published 1996 Journal Zhongguo Yao Li Xue Bao Section Body Doc Link 9772675 Disease Relevance 0 Pain Relevance 0
Augmentation of TNF-alpha production, NK cell activity and IL-12 p35 mRNA expression by methionine enkephalin.
Positive_regulation (Augmentation) of Transcription (expression) of IL-12 in NK cell associated with enkephalin
4) Confidence 0.16 Published 1996 Journal Zhongguo Yao Li Xue Bao Section Title Doc Link 9772675 Disease Relevance 0 Pain Relevance 0.24

General Comments

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