INT77959

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Context Info
Confidence 0.04
First Reported 1998
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.26
Pain Relevance 0.27

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
kidney 1
Rare1 (Mus musculus)
Pain Link Frequency Relevance Heat
cINOD 3 89.20 High High
cytokine 13 77.76 Quite High
agonist 12 70.24 Quite High
alcohol 1 66.40 Quite High
Spinal cord 32 62.00 Quite High
Inflammation 46 38.36 Quite Low
Enkephalin 1 25.00 Low Low
corticosteroid 1 18.16 Low Low
Central nervous system 17 5.00 Very Low Very Low Very Low
Inflammatory response 10 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 56 93.88 High High
Deafness 5 89.84 High High
INFLAMMATION 62 88.80 High High
Diabetes Mellitus 7 65.28 Quite High
Frailty 20 62.00 Quite High
Leukemia 1 59.28 Quite High
Polycystic Ovary Syndrome 6 56.72 Quite High
Contusions 2 52.80 Quite High
Reprotox - General 3 1 52.48 Quite High
Injury 20 52.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It

interacts with retinoic acid response elements (RARE) in the promoters of

RARE Binding (interacts) of
1) Confidence 0.04 Published 2007 Journal PPAR Research Section Body Doc Link PMC1950239 Disease Relevance 0.64 Pain Relevance 0.14
A monkey kidney cDNA that encodes a nuclear regulatory factor was identified by expression and affinity binding to a synthetic retinoic acid response element (RARE) and was used to isolate human placental and rat germ cell cDNAs by hybridization.
RARE Binding (binding) of in kidney
2) Confidence 0.01 Published 1998 Journal Mol. Endocrinol. Section Abstract Doc Link 9773984 Disease Relevance 0.30 Pain Relevance 0
This transcription factor heterodimerizes with the 9, cis-retinoic acid receptor (RXR) and binds to a short sequence of DNA, a PPAR response element (PPRE), present in the promoter region of target genes.
PPAR response element Binding (binds) of
3) Confidence 0.00 Published 2009 Journal Reprod Biol Endocrinol Section Body Doc Link PMC2795759 Disease Relevance 0.32 Pain Relevance 0.12

General Comments

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