INT77962

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Context Info
Confidence 0.27
First Reported 1998
Last Reported 1998
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.47
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (DEAF1) nucleus (DEAF1) DNA binding (DEAF1)
cytoplasm (DEAF1)
DEAF1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Enkephalin 2 25.00 Low Low
Disease Link Frequency Relevance Heat
Deafness 10 95.20 Very High Very High Very High
Leukemia 2 39.92 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our data suggests that NUDR may activate transcription independently of promoter binding, perhaps through protein-protein interaction with basal transcription factors, or by activation of secondary factors.
NUDR Binding (binding) of
1) Confidence 0.27 Published 1998 Journal Mol. Endocrinol. Section Abstract Doc Link 9773984 Disease Relevance 0.24 Pain Relevance 0
The derived consensus- binding motif recognized by NUDR (TTCGGGNNTTTCCGG) was confirmed by mobility shift and deoxyribonuclease I (DNase I) protection assays; however, the consensus sequence was also unable to confer NUDR-dependent transcriptional activation to the thymidine kinase promoter.
NUDR Binding (recognized) of
2) Confidence 0.18 Published 1998 Journal Mol. Endocrinol. Section Abstract Doc Link 9773984 Disease Relevance 0.23 Pain Relevance 0

General Comments

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