INT78044

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Context Info
Confidence 0.52
First Reported 1998
Last Reported 2010
Negated 2
Speculated 0
Reported most in Abstract
Documents 9
Total Number 15
Disease Relevance 12.30
Pain Relevance 1.76

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
muscles 7
coronary artery 1
Tnnc1 (Mus musculus)
Pain Link Frequency Relevance Heat
Angina 14 98.64 Very High Very High Very High
ischemia 83 98.08 Very High Very High Very High
Inflammatory response 13 92.24 High High
Percutaneous transluminal coronary angioplasty 5 92.08 High High
fibrosis 14 86.64 High High
Inflammation 65 82.56 Quite High
cytokine 72 53.56 Quite High
anesthesia 14 5.00 Very Low Very Low Very Low
chemokine 7 5.00 Very Low Very Low Very Low
Sciatic nerve 7 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Reperfusion Injury 322 100.00 Very High Very High Very High
Myocardial Infarction 47 99.60 Very High Very High Very High
Cv General 3 Under Development 11 98.64 Very High Very High Very High
Systemic Inflammatory Response Syndrome 68 98.24 Very High Very High Very High
Cv Unclassified Under Development 124 98.08 Very High Very High Very High
Angina 3 98.08 Very High Very High Very High
Pyometra 68 97.56 Very High Very High Very High
Fatigue 56 97.40 Very High Very High Very High
Coronary Artery Disease 6 95.64 Very High Very High Very High
Death 68 91.84 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
As a group, there was no significant change in the cTnI concentrations before and after surgery in the 46 dogs with pyometra.
Neg (no) Regulation (change) of cTnI associated with pyometra
1) Confidence 0.52 Published 2008 Journal Acta Vet Scand Section Body Doc Link PMC2546406 Disease Relevance 1.04 Pain Relevance 0
The cTnI concentrations in the 13 dogs with increased preoperative cTnI concentrations decreased in 8 dogs, increased in 4 dogs, and was unchanged in one dog.
Neg (unchanged) Regulation (unchanged) of cTnI
2) Confidence 0.44 Published 2008 Journal Acta Vet Scand Section Abstract Doc Link PMC2546406 Disease Relevance 0.92 Pain Relevance 0.14
In conclusion, these data demonstrate a relatively high sensitivity of CTnI, CK-MBmass and Mb in early diagnosis of AMI.
Regulation (sensitivity) of CTnI associated with myocardial infarction
3) Confidence 0.25 Published 2000 Journal Hua Xi Yi Ke Da Xue Xue Bao Section Abstract Doc Link 12515148 Disease Relevance 0.81 Pain Relevance 0.05
The CTnI, CK-MBmass and Mb values in group AMI were significantly higher than those in groups of UA and SM.
Regulation (values) of CTnI associated with myocardial infarction
4) Confidence 0.11 Published 2000 Journal Hua Xi Yi Ke Da Xue Xue Bao Section Abstract Doc Link 12515148 Disease Relevance 1.20 Pain Relevance 0.08
Diagnostic performance was evaluated for peak values of CK-MB and cTnI obtained during the first 24 hours for the combined end point of acute myocardial infarction and/or major cardiac events within 72 hours.
Regulation (values) of cTnI associated with myocardial infarction
5) Confidence 0.11 Published 1999 Journal Am. J. Cardiol. Section Abstract Doc Link 10215279 Disease Relevance 0.35 Pain Relevance 0.17
This study assessed the prognostic value of cardiac troponin I (cTnI) and C-reactive protein (CRP) in unstable angina, and specifically in patients with angiographically proven coronary artery disease.
Regulation (value) of cTnI in coronary artery associated with angina and coronary artery disease
6) Confidence 0.06 Published 1998 Journal Am. J. Cardiol. Section Abstract Doc Link 9781965 Disease Relevance 0.73 Pain Relevance 0.44
In contrast to Carvalho et al. [7], Fish et al. [8] found that full muscle recovery was not reached 42 days after 2 hours of ischemia since maximal force production was still reduced in ischemic-reperfused muscles as compared to control muscles in rats.
Regulation (control) of muscles in muscles associated with ischemia
7) Confidence 0.06 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2866363 Disease Relevance 1.76 Pain Relevance 0.10
None of the patients had abnormal cTnI or cTnT levels, CK activity, or CKMB levels before the procedures.
Regulation (abnormal) of cTnI
8) Confidence 0.05 Published 2000 Journal Med. Sci. Monit. Section Abstract Doc Link 11208396 Disease Relevance 0.45 Pain Relevance 0.29
By 14 days, absolute maximal force (P0, Figure 2), specific maximal force (P0/m, Figure 3), fatigue resistance (FR, Figure 4) and muscle weight (Figure 5) were still markedly reduced in ischemic/reperfused muscles as compared to control muscles (P < .05).
Regulation (control) of muscles in muscles associated with fatigue
9) Confidence 0.04 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2866363 Disease Relevance 0.92 Pain Relevance 0.04
17.5%) as compared to control muscles.
Regulation (control) of muscles in muscles
10) Confidence 0.04 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2866363 Disease Relevance 1.21 Pain Relevance 0.07
However, specific maximal force (Figure 3) was still reduced in ischemic/reperfused muscles as compared to control muscles, by day 56 (P < .05).
Regulation (control) of muscles in muscles
11) Confidence 0.04 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2866363 Disease Relevance 0.46 Pain Relevance 0
75%, resp.) as compared to control muscles (P < .05).
Regulation (control) of muscles in muscles
12) Confidence 0.04 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Abstract Doc Link PMC2866363 Disease Relevance 0.52 Pain Relevance 0.08
The overall diagnostic sensitivity of cTnI was 83.1%, and 84.8% for cTnT (quantitative), 72.3% for cTnT(qualitative), 64.8% for H-FABP, 81.8% for CK and 59.3% for CK-MB.
Regulation (sensitivity) of cTnI
13) Confidence 0.03 Published 2002 Journal Rinsho Byori Section Abstract Doc Link 12451679 Disease Relevance 0.85 Pain Relevance 0.24
Values of IR muscles and myotoxin-treated muscles were also expressed as a percentage of control (normal) muscles, that is, contralateral muscles.
Regulation (Values) of muscles in muscles associated with reperfusion injury
14) Confidence 0.02 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2866363 Disease Relevance 0.53 Pain Relevance 0.03
Values of IR muscles and myotoxin-treated muscles were also expressed as a percentage of control (normal) muscles, that is, contralateral muscles.
Regulation (Values) of muscles in muscles associated with reperfusion injury
15) Confidence 0.02 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2866363 Disease Relevance 0.54 Pain Relevance 0.03

General Comments

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