INT78121

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Context Info
Confidence 0.23
First Reported 1998
Last Reported 1998
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.61
Pain Relevance 0.40

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (App) Golgi apparatus (App) plasma membrane (App)
extracellular matrix organization (App) DNA binding (App) cytoplasm (App)
App (Mus musculus)
20S (Mus musculus)
Pain Link Frequency Relevance Heat
Abeta 6 100.00 Very High Very High Very High
adenocard 1 76.64 Quite High
cINOD 1 72.00 Quite High
Inflammation 4 50.76 Quite High
cytokine 1 43.80 Quite Low
Disease Link Frequency Relevance Heat
Alzheimer's Dementia 2 88.32 High High
Death 1 80.00 Quite High
Disease 6 75.00 Quite High
INFLAMMATION 4 70.56 Quite High
Neuroblastoma 1 54.08 Quite High
Adhesions 1 45.04 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We postulate that PG-induced elevation of Abeta may lead to an increased binding of Abeta to the 20S proteasome, resulting in a reduction of 20S proteasome-mediated degradation of ubiquitin-conjugated proteins.
Positive_regulation (increased) of Abeta Binding (binding) of 20S associated with abeta
1) Confidence 0.23 Published 1998 Journal Proc. Soc. Exp. Biol. Med. Section Abstract Doc Link 9790168 Disease Relevance 0.61 Pain Relevance 0.40

General Comments

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