INT78193

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Context Info
Confidence 0.19
First Reported 1998
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.31
Pain Relevance 0.31

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Tnc) extracellular space (Tnc) extracellular region (Tnc)
cell adhesion (Tnc) proteinaceous extracellular matrix (Tnc)
Anatomy Link Frequency
tooth 1
Tnc (Mus musculus)
Pain Link Frequency Relevance Heat
antagonist 3 97.72 Very High Very High Very High
fluoxetine 1 95.48 Very High Very High Very High
Serotonin 2 75.00 Quite High
Inflammatory response 4 5.00 Very Low Very Low Very Low
Inflammation 3 5.00 Very Low Very Low Very Low
ischemia 2 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Spinal cord 1 5.00 Very Low Very Low Very Low
midbrain 1 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 31 92.72 High High
Death 51 82.96 Quite High
Optic Nerve Injuries 34 75.00 Quite High
Injury 32 64.08 Quite High
Necrosis 5 25.00 Low Low
Cancer 5 25.00 Low Low
Ganglion Cysts 3 25.00 Low Low
INFLAMMATION 7 5.00 Very Low Very Low Very Low
Retina Disease 4 5.00 Very Low Very Low Very Low
Stress 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In contrast serotonergic modulation of S-100beta and tenascin expression was not reversed by any of the 5-HT receptor antagonists tested, although the 5-HT uptake inhibitor, fluoxetine, did reverse the effect of 5-HT on S-100beta expression, as well as tooth-germ development.
Regulation (modulation) of tenascin in tooth associated with antagonist and fluoxetine
1) Confidence 0.19 Published 1998 Journal Arch. Oral Biol. Section Abstract Doc Link 9796780 Disease Relevance 0 Pain Relevance 0.31
Arrays were validated by means of quantative reverse transcription polymerase chain reaction (qRT–PCR) on ten regulated genes at two times post-lesion.
Regulation (regulated) of ten
2) Confidence 0.01 Published 2008 Journal Molecular Vision Section Abstract Doc Link PMC2426719 Disease Relevance 0.31 Pain Relevance 0

General Comments

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