INT78201

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Context Info
Confidence 0.02
First Reported 1998
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.79
Pain Relevance 0.48

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

methyltransferase activity (MLL) nucleus (MLL) protein complex assembly (MLL)
DNA binding (MLL)
MLL (Homo sapiens)
Pain Link Frequency Relevance Heat
Sciatic nerve 3 94.28 High High
Neuritis 4 90.32 High High
Inflammation 2 83.08 Quite High
Action potential 1 50.64 Quite High
Demyelination 1 25.00 Low Low
Potency 5 5.00 Very Low Very Low Very Low
isoflurane 2 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
medulla 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Experimental Autoimmune Neuritis 4 90.32 High High
Dejerine-sottas Disease 1 89.16 High High
Immunization 2 83.76 Quite High
Neuropathic Pain 1 83.52 Quite High
INFLAMMATION 1 83.08 Quite High
Infection 49 69.92 Quite High
Viral Meningitis 11 52.88 Quite High
Asymptomatic Infections 1 33.60 Quite Low
Disease 15 27.04 Quite Low
Recurrence 2 26.16 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Ten Lewis rats were immunized with purified PMP22 fusion protein (50-100 microg) and eight controls with the same amount of GST.
Regulation (controls) of fusion protein
1) Confidence 0.02 Published 1998 Journal Brain Section Abstract Doc Link 9798745 Disease Relevance 0.67 Pain Relevance 0.48
Each step, from the interaction of the receptor-binding protein with its receptor and the subsequent triggering of the fusion protein, to the conformational changes in the fusion protein that lead to fusion readiness, and the refolding of the fusion protein that drives membrane merger, are potential targets for antiviral compounds.
Regulation (changes) of fusion protein
2) Confidence 0.01 Published 2010 Journal PLoS Pathogens Section Body Doc Link PMC2965769 Disease Relevance 0.12 Pain Relevance 0

General Comments

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