INT78227

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Context Info
Confidence 0.43
First Reported 1998
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 2.54
Pain Relevance 0.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Mbp) nucleus (Mbp) cytoplasm (Mbp)
Anatomy Link Frequency
T cells 4
perirhinal cortex 2
Mbp (Mus musculus)
Pain Link Frequency Relevance Heat
Neuritis 2 92.48 High High
Multiple sclerosis 6 89.60 High High
Spinal cord 10 82.92 Quite High
metalloproteinase 65 50.00 Quite Low
Abeta 1 50.00 Quite Low
Central nervous system 30 48.72 Quite Low
chemokine 6 25.16 Quite Low
anesthesia 1 21.36 Low Low
Eae 4 15.84 Low Low
cytokine 10 5.64 Low Low
Disease Link Frequency Relevance Heat
Multiple Sclerosis 51 99.28 Very High Very High Very High
Paralysis 7 96.80 Very High Very High Very High
Optic Neuritis 1 92.48 High High
Demyelinating Disease 3 89.60 High High
Disease 19 84.60 Quite High
Rheumatoid Arthritis 2 83.96 Quite High
Mycobacterial Infection 2 83.68 Quite High
Experimental Autoimmune Encephalomyelitis 3 75.00 Quite High
Autoimmune Disease 1 72.08 Quite High
Urological Neuroanatomy 3 68.40 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Seven days after the passive transfer of myelin basic protein (MBP)-reactive T cell blasts, we observed a significant infiltration of eosinophils into the optic nerves of the mice.
Positive_regulation (transfer) of Gene_expression (transfer) of MBP in T cell
1) Confidence 0.43 Published 1998 Journal Lab. Invest. Section Abstract Doc Link 9800949 Disease Relevance 1.12 Pain Relevance 0.25
(25–35)-injected mice receiving vehicle, and administration of Kihi-to resulted in an increase in MBP expression levels in the perirhinal cortex (Figures 6 and 7).


Positive_regulation (increase) of Gene_expression (expression) of MBP in perirhinal cortex
2) Confidence 0.38 Published 2008 Journal BMC Complement Altern Med Section Body Doc Link PMC2532680 Disease Relevance 0.07 Pain Relevance 0
AT-EAE in SJL mice was induced by passive transfer of MBP-reactive T cells as described previously [17].
Positive_regulation (transfer) of Gene_expression (transfer) of MBP in T cells associated with multiple sclerosis
3) Confidence 0.32 Published 2007 Journal J Neuroinflammation Section Body Doc Link PMC2075488 Disease Relevance 1.35 Pain Relevance 0

General Comments

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