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Context Info
Confidence 0.13
First Reported 1992
Last Reported 1992
Negated 0
Speculated 1
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.49

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signal transduction (Adra2a) plasma membrane (Adra2a) carbohydrate metabolic process (Man2a2)
cytoplasm (Adra2a) signal transducer activity (Adra2a)
Man2a2 (Rattus norvegicus)
Adra2a (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Clonidine 3 91.76 High High
antagonist 4 88.12 High High
agonist 3 68.08 Quite High


Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These results suggest that in rats islet glucagon release induced by alpha adrenoceptor agonism is mediated through alpha-2 adrenoceptors, possibly the alpha-2A subtype.
alpha-2 Spec (possibly) Positive_regulation (mediated) of alpha-2A
1) Confidence 0.13 Published 1992 Journal Acta Endocrinol. Section Abstract Doc Link 1357904 Disease Relevance 0 Pain Relevance 0.49

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