INT78533

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Context Info
Confidence 0.55
First Reported 1998
Last Reported 2010
Negated 0
Speculated 1
Reported most in Abstract
Documents 2
Total Number 3
Disease Relevance 1.93
Pain Relevance 0.92

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (COL4A4)
Anatomy Link Frequency
macrophages 1
basement membrane 1
pancreatic ducts 1
COL4A4 (Homo sapiens)
Pain Link Frequency Relevance Heat
metalloproteinase 20 97.64 Very High Very High Very High
Chronic pancreatitis 9 97.16 Very High Very High Very High
fibrosis 1 96.20 Very High Very High Very High
palliative 1 85.56 High High
Inflammation 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pancreatitis 11 97.16 Very High Very High Very High
Fibrosis 2 96.20 Very High Very High Very High
Cancer 121 90.52 High High
Adenocarcinoma 1 73.76 Quite High
Heart Rate Under Development 3 73.12 Quite High
Stomach Cancer 27 66.36 Quite High
Metastasis 12 5.00 Very Low Very Low Very Low
Disease 8 5.00 Very Low Very Low Very Low
Recurrence 7 5.00 Very Low Very Low Very Low
Malignant Neoplastic Disease 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Immunohistochemical localization of type IV collagen alpha chains in the basement membrane of the pancreatic duct in human normal pancreas and pancreatic diseases.
Localization (localization) of type IV collagen in basement membrane associated with pancreatitis
1) Confidence 0.55 Published 2004 Journal Pancreas Section Title Doc Link 15211113 Disease Relevance 0.83 Pain Relevance 0.22
Immunolocalization of MMP9, MMP2, type IV Collagen, macrophages and CD105 were performed using streptavidin-biotin peroxidase complex method (SP).
Localization (Immunolocalization) of IV Collagen in macrophages
2) Confidence 0.29 Published 2010 Journal J Transl Med Section Body Doc Link PMC2965128 Disease Relevance 0.53 Pain Relevance 0.09
To reach a better understanding of this problem, we investigated the immunolocalizations of type IV collagen (Col-IV) and laminin around pancreatic ducts, and those of matrix metalloproteinase-2,9 (MMP-2,9), tissue inhibitors of metalloproteinase-1,2), and transforming growth factor-beta 1 (TGF beta 1) at the ductal epithelia in chronic pancreatitis.
Spec (investigated) Localization (immunolocalizations) of Col-IV in pancreatic ducts associated with metalloproteinase and chronic pancreatitis
3) Confidence 0.01 Published 1998 Journal Pancreas Section Abstract Doc Link 9821184 Disease Relevance 0.57 Pain Relevance 0.61

General Comments

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