INT78621

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Context Info
Confidence 0.06
First Reported 1998
Last Reported 2002
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.50
Pain Relevance 0.39

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (PRL, INS) cell proliferation (PRL) cytosol (PRL)
extracellular space (INS) small molecule metabolic process (INS) carbohydrate metabolic process (INS)
PRL (Homo sapiens)
INS (Homo sapiens)
Pain Link Frequency Relevance Heat
Somatostatin 2 87.84 High High
Clonidine 1 84.08 Quite High
dexamethasone 1 82.32 Quite High
Neurotransmitter 1 78.40 Quite High
Central nervous system 1 76.12 Quite High
Neuropeptide 1 64.64 Quite High
agonist 1 56.24 Quite High
Lasting pain 1 50.40 Quite High
antagonist 1 48.64 Quite Low
depression 1 42.56 Quite Low
Disease Link Frequency Relevance Heat
Nociception 1 95.96 Very High Very High Very High
Epilepsy 1 95.08 Very High Very High Very High
Disease 3 90.24 High High
Nervous System Injury 1 85.52 High High
Pain 1 50.40 Quite High
Depression 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Galanin has also been shown to increase the levels of growth hormone, prolactin and luteinizing hormone, to inhibit glucose induced insulin release and to affect gastrointestinal motility.
prolactin Positive_regulation (induced) of Localization (release) of insulin
1) Confidence 0.06 Published 2002 Journal Curr Drug Targets CNS Neurol Disord Section Abstract Doc Link 12769595 Disease Relevance 0.50 Pain Relevance 0.19
Glucagon (1 microM), ACTH (2.5 microM), human and bovine growth hormone (4.6 and 2.1 microM), prolactin (0.27 microM), corticosterone (0.4 microM), androstanolone (10(-2) microM), estradiol and estrone (10 microM), triiodothyronine and thyroxine (1 microM) enhanced significantly the glucose-induced insulin secretion.
prolactin Positive_regulation (enhanced) of Localization (secretion) of insulin
2) Confidence 0.04 Published 1998 Journal Comp. Biochem. Physiol. C, Pharmacol. Toxicol. Endocrinol. Section Abstract Doc Link 9827019 Disease Relevance 0 Pain Relevance 0.20

General Comments

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