INT78661

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Context Info
Confidence 0.24
First Reported 1998
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 1.23
Pain Relevance 0.51

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Dlst) plasma membrane (Dlst) nucleus (Dlst)
transferase activity, transferring acyl groups (Dlst) cytoplasm (Dlst)
Anatomy Link Frequency
stroma 2
mammary gland 2
brain 2
Dlst (Rattus norvegicus)
Pain Link Frequency Relevance Heat
endometriosis 168 81.40 Quite High
ischemia 4 75.00 Quite High
Neuronal nitric oxide synthase 2 75.00 Quite High
Pain 17 72.80 Quite High
anesthesia 5 64.72 Quite High
isoflurane 1 55.20 Quite High
withdrawal 1 47.88 Quite Low
cytokine 27 14.40 Low Low
Inflammation 44 5.00 Very Low Very Low Very Low
substance P 21 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Endometriosis 224 99.04 Very High Very High Very High
Cancer 13 91.60 High High
Repression 3 90.72 High High
Cv Unclassified Under Development 4 75.00 Quite High
Body Weight 12 67.56 Quite High
Apoptosis 5 62.68 Quite High
Increased Venous Pressure Under Development 1 45.28 Quite Low
Disease 25 39.40 Quite Low
Nicotine Addiction 1 27.60 Quite Low
INFLAMMATION 44 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Therefore, we performed proliferation-specific analyses and determined expression of the progesterone receptor (PR), which is stimulated in the mammary gland after E2 exposure (Tekmal et al. 2005).
Positive_regulation (stimulated) of Gene_expression (exposure) of E2 in mammary gland
1) Confidence 0.24 Published 2007 Journal Environ Health Perspect Section Body Doc Link PMC2174401 Disease Relevance 0.22 Pain Relevance 0.15
One possible mechanism may relate to E2 enhancing brain nNOS expression and activity.
Positive_regulation (enhancing) of Gene_expression (expression) of E2 in brain
2) Confidence 0.19 Published 1998 Journal Neuroreport Section Abstract Doc Link 9831465 Disease Relevance 0.17 Pain Relevance 0.14
AR mRNA was down-regulated by both doses of E2 in controls, whereas 4-MBC-exposed animals responded to only 10 ?
Positive_regulation (doses) of Gene_expression (doses) of E2
3) Confidence 0.05 Published 2007 Journal Environ Health Perspect Section Body Doc Link PMC2174398 Disease Relevance 0 Pain Relevance 0
Moreover, the enzyme aromatase is exclusively found in endometriotic stroma [105] and provides E1, which is further converted to E2 by 17?
Positive_regulation (converted) of Gene_expression (converted) of E2 in stroma associated with endometriosis
4) Confidence 0.03 Published 2007 Journal Semin Immunopathol Section Body Doc Link PMC2668599 Disease Relevance 0.84 Pain Relevance 0.22

General Comments

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