INT78669

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Context Info
Confidence 0.33
First Reported 1998
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.45
Pain Relevance 0.79

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (CYP2C18) endoplasmic reticulum (CYP2C18)
Anatomy Link Frequency
liver 1
CYP2C18 (Homo sapiens)
Pain Link Frequency Relevance Heat
Fibrositis 8 99.82 Very High Very High Very High
Pain 6 99.76 Very High Very High Very High
lidocaine 1 86.68 High High
Disease Link Frequency Relevance Heat
Sleep Disorders 6 99.82 Very High Very High Very High
Pain 6 99.76 Very High Very High Very High
Liver Disease 6 99.44 Very High Very High Very High
Anxiety Disorder 1 66.32 Quite High
Cognitive Disorder 1 55.44 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A random sample of patients with FM (N=409) completed the CPCI, the Pain Catastrophizing Scale (PCS), the Physical Index of the Fibromyalgia Impact Questionnaire (FIQ-PH) and the Pain Disability Index (PDI).
Negative_regulation (completed) of CPCI associated with pain and fibrositis
1) Confidence 0.33 Published 2009 Journal Pain Section Abstract Doc Link 19716234 Disease Relevance 1.07 Pain Relevance 0.71
The metabolism of the probe drugs used in non-genetic P450 function tests in patients with liver disease falls into two categories: reduced (CYP1A2, CYP2C, 2E1 and 3A) and unchanged (CYP2C).
Negative_regulation (reduced) of CYP2C in liver associated with liver disease
2) Confidence 0.08 Published 1998 Journal J Clin Pharm Ther Section Abstract Doc Link 9831966 Disease Relevance 0.39 Pain Relevance 0.09

General Comments

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