INT78704

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Context Info
Confidence 0.37
First Reported 1998
Last Reported 2010
Negated 1
Speculated 2
Reported most in Body
Documents 10
Total Number 11
Disease Relevance 11.38
Pain Relevance 1.44

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (CCL11) extracellular space (CCL11) extracellular region (CCL11)
cell adhesion (CCL11) cytoskeleton organization (CCL11)
Anatomy Link Frequency
eosinophil 3
coronary artery 1
monocyte 1
Cerebrospinal fluid 1
CCL11 (Homo sapiens)
Pain Link Frequency Relevance Heat
Angina 9 95.28 Very High Very High Very High
Spinal cord 2 95.00 High High
chemokine 15 94.52 High High
headache 1 91.16 High High
cytokine 29 90.88 High High
Inflammation 28 86.00 High High
fibrosis 10 82.96 Quite High
pain pelvic 2 81.76 Quite High
aspirin 8 50.00 Quite Low
cINOD 3 25.00 Low Low
Disease Link Frequency Relevance Heat
Eosinophilic Esophagitis 212 100.00 Very High Very High Very High
Asthma 87 100.00 Very High Very High Very High
Rhinitis 73 100.00 Very High Very High Very High
Meningitis 3 100.00 Very High Very High Very High
Uterine Fibroids 12 99.60 Very High Very High Very High
Coronary Artery Disease 6 98.28 Very High Very High Very High
Disease 61 97.68 Very High Very High Very High
Acute Coronary Syndrome 9 96.64 Very High Very High Very High
Brain Disease 1 96.00 Very High Very High Very High
Eosinophilia 38 95.60 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Association between eotaxin (CCL11), C-reactive protein, and antimicrobial antibodies in patients undergoing coronary angioplasty.
eotaxin Binding (Association) of
1) Confidence 0.37 Published 2006 Journal J. Investig. Med. Section Title Doc Link 17169268 Disease Relevance 0.87 Pain Relevance 0.13
Eotaxin concentrations at inclusion were higher in patients with coronary artery disease than in control patients, p = .01, and comparable in patients with stable angina and those with acute coronary syndrome but did not correlate with C-reactive protein.
Eotaxin Binding (concentrations) of in coronary artery associated with acute coronary syndrome, angina and coronary artery disease
2) Confidence 0.37 Published 2006 Journal J. Investig. Med. Section Abstract Doc Link 17169268 Disease Relevance 1.35 Pain Relevance 0.27
Association between eotaxin (CCL11), C-reactive protein, and antimicrobial antibodies in patients undergoing coronary angioplasty.
CCL11 Binding (Association) of
3) Confidence 0.37 Published 2006 Journal J. Investig. Med. Section Title Doc Link 17169268 Disease Relevance 0.87 Pain Relevance 0.13
There was no consistent association between the presence of eosinophils and either IL-5 or eotaxin in smooth muscle cells, suggesting that mechanisms other than IL-5 or eotaxin production may account for the eosinophilia.
eotaxin Neg (no) Binding (association) of in eosinophils associated with eosinophilia
4) Confidence 0.36 Published 2001 Journal Int. J. Gynecol. Pathol. Section Abstract Doc Link 11444199 Disease Relevance 1.73 Pain Relevance 0.12
We also performed immunohistochemical and in situ hybridization studies to assess for interleukin-5 (IL-5) and eotaxin in these LMs.
eotaxin Binding (assess) of associated with uterine fibroids
5) Confidence 0.36 Published 2001 Journal Int. J. Gynecol. Pathol. Section Abstract Doc Link 11444199 Disease Relevance 1.72 Pain Relevance 0.12
Cerebrospinal fluid eotaxin and eotaxin-2 levels in human eosinophilic meningitis associated with angiostrongyliasis.
eotaxin Binding (associated) of in Cerebrospinal fluid associated with rhinitis and meningitis
6) Confidence 0.36 Published 2007 Journal Cytokine Section Title Doc Link 17703945 Disease Relevance 0.92 Pain Relevance 0.21
When expressed in stable transfectants, this receptor bound 125I-labeled guinea pig eotaxin, 125I-labeled human monocyte chemotactic protein-3, and 125I-labeled human RANTES.
eotaxin Binding (bound) of in monocyte
7) Confidence 0.35 Published 1998 Journal J. Immunol. Section Abstract Doc Link 9834099 Disease Relevance 0.17 Pain Relevance 0.21
Specifically, we focused on examining immune indicators associated with EoE, for example, eotaxin and FGF.
eotaxin Spec (examining) Binding (associated) of associated with eosinophilic esophagitis
8) Confidence 0.09 Published 2010 Journal Allergy Asthma Clin Immunol Section Body Doc Link PMC2976489 Disease Relevance 0.82 Pain Relevance 0
Eotaxin mediates some of its biological effects by binding to the receptor CCR3 on the eosinophil.
Eotaxin Binding (binding) of in eosinophil
9) Confidence 0.07 Published 2004 Journal Clin Mol Allergy Section Body Doc Link PMC425596 Disease Relevance 0.72 Pain Relevance 0.26
Specifically, we focused on examining immune indicators associated with EoE, for example, eotaxin and FGF.
eotaxin Spec (examining) Binding (associated) of associated with eosinophilic esophagitis
10) Confidence 0.07 Published 2010 Journal Allergy Asthma Clin Immunol Section Body Doc Link PMC2976489 Disease Relevance 0.82 Pain Relevance 0
Association of the AIA phenotype (total eosinophil count, rhinosinusitis, FEV1, eotaxin-1) with IL-13 polymorphisms
eotaxin-1 Binding (Association) of in eosinophil associated with asthma
11) Confidence 0.04 Published 2010 Journal Allergy, Asthma & Immunology Research Section Body Doc Link PMC2846737 Disease Relevance 1.38 Pain Relevance 0

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